furanether B

Base Information

• Chemical Name: furanether B
• CAS No.: 123164-81-8
• Molecular Formula: C₁₅H₂₀O₂
• Molecular Weight: 232.323
• Mol file: 123164-81-8.mol

Synonyms:

Chemical Property of furanether B

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of furanether B

There total 5 articles about furanether B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,5S)-4-[1-Hydroxy-meth-(Z)-ylidene]-1-methyl-8-oxa-bicyclo[3.2.1]oct-6-en-3-one (127786-92-9) → furanether B (72601-35-5,74778-23-7,123164-81-8)

Guidance literature:

Multi-step reaction with 3 steps

1: p-TsOH / benzene / 3 h / 80 °C

2: 1.) 50 percent NaOH, 2.) 2N HCl / 1.) CH₂Cl₂, 44 h, 48 deg C, then 24 h, rt, 2.) THF, 3 h, rt

With hydrogenchloride; sodium hydroxide; toluene-4-sulfonic acid; In benzene;

DOI:10.1016/S0040-4039(01)93491-4

Reference yield:

(1R*,5S*)-1-methyl-8-oxabicyclo<3.2.1>oct-6-en-3-one (73350-65-9,89920-04-7,111407-72-8) → furanether B (72601-35-5,74778-23-7,123164-81-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 84 percent / NaOEt / benzene / 18 h / Ambient temperature

2: p-TsOH / benzene / 3 h / 80 °C

3: 1.) 50 percent NaOH, 2.) 2N HCl / 1.) CH₂Cl₂, 44 h, 48 deg C, then 24 h, rt, 2.) THF, 3 h, rt

With hydrogenchloride; sodium hydroxide; sodium ethanolate; toluene-4-sulfonic acid; In benzene;

DOI:10.1016/S0040-4039(01)93491-4

Reference yield:

(1S,5S)-4-[1-Butylsulfanyl-meth-(E)-ylidene]-1-methyl-8-oxa-bicyclo[3.2.1]oct-6-en-3-one (127818-25-1,127818-26-2) → furanether B (72601-35-5,74778-23-7,123164-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 50 percent NaOH, 2.) 2N HCl / 1.) CH₂Cl₂, 44 h, 48 deg C, then 24 h, rt, 2.) THF, 3 h, rt

With hydrogenchloride; sodium hydroxide;

DOI:10.1016/S0040-4039(01)93491-4

upstream raw materials:

carbon monoxide

(1S,8S)-8-Methyl-4,11-dioxa-tricyclo[6.2.1.0^2,6]undeca-2,5,9-triene

prop-1-yne

methyl iodide