1-METHOXYPHTHALAZINE

Base Information

• Chemical Name: 1-METHOXYPHTHALAZINE
• CAS No.: 24953-56-8
• Molecular Formula: C9H8 N2 O
• Molecular Weight: 160.175
• Hs Code.: 2933990090
• Mol file: 24953-56-8.mol

Synonyms:1-Methoxyphthalazine

Chemical Property of 1-METHOXYPHTHALAZINE

Chemical Property:

• Vapor Pressure: 3.37E-05mmHg at 25°C
• Boiling Point: 365.1°Cat760mmHg
• Flash Point: 133.1°C
• PSA: 35.01000
• Density: 1.195g/cm³
• LogP: 1.63840

Purity/Quality:

99% ^*data from raw suppliers

1-METHOXYPHTHALAZINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Methoxyphthalazine is a useful anti-corrosion agent.

Technology Process of 1-METHOXYPHTHALAZINE

There total 6 articles about 1-METHOXYPHTHALAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 1-chlorophthalazine (5784-45-2) → 1-methoxyphthalazine (24953-56-8)

Guidance literature:

methanol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.25h;

1-chlorophthalazine; In tetrahydrofuran; at 50 ℃; for 12h;

DOI:10.1021/acs.orglett.2c00127

Reference yield:

o-carboxybenzaldehyde (119-67-5) → 1-methoxyphthalazine (24953-56-8)

Guidance literature:

Multi-step reaction with 3 steps

2: phosphorus oxychloride

With trichlorophosphate;

Reference yield:

phthalazone (119-39-1) → 1-methoxyphthalazine (24953-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus oxychloride

With trichlorophosphate;

upstream raw materials:

methanol

1-chlorophthalazine

sodium methylate

phthalazone

Downstream raw materials:

1-ethoxyphthalazine

4-isopropylidene-7-methoxy-1,1-dimethyl-1,11b-dihydro-[1,3]oxazino[4,3-a]phthalazin-2-one

α-Phenyl-1-phthalazinacetonitril

1-benzoylphthalazine