3,4-diphenylthiophene-2,5-dicarboxylic acid

Base Information

• Chemical Name: 3,4-diphenylthiophene-2,5-dicarboxylic acid
• CAS No.: 19799-42-9
• Molecular Formula: C18H12 O4 S
• Molecular Weight: 324.3505
• Mol file: 19799-42-9.mol

Synonyms:3,4-Diphenyl-2,5-dicarboxythiophene;3,4-Diphenyl-2,5-thiophenedicarboxylic acid; NSC 219449; NSC 403641

Chemical Property of 3,4-diphenylthiophene-2,5-dicarboxylic acid

Chemical Property:

• Vapor Pressure: 4.14E-08mmHg at 25°C
• Boiling Point: 428.6°C at 760 mmHg
• Flash Point: 213°C
• Density: 1.382g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-diphenylthiophene-2,5-dicarboxylic acid

There total 4 articles about 3,4-diphenylthiophene-2,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

diethyl thioglycolate (925-47-3) + benzil (134-81-6) → 3,4-bis(phenyl)thiophene-2,5-dicarboxylic acid (19799-42-9)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 72h;

DOI:10.1021/ma047940e

Reference yield:

diethyl thioglycolate (925-47-3) + benzil (134-81-6) → 3,4-bis(phenyl)thiophene-2,5-dicarboxylic acid (19799-42-9)

Guidance literature:

With methanol; sodium methylate;

Reference yield:

thiodiacetic acid (123-93-3) + isopropyl chloroformate (108-23-6) + benzil (134-81-6) → C21H18O4S + 3,4-bis(phenyl)thiophene-2,5-dicarboxylic acid (19799-42-9)

Guidance literature:

Multistep reaction.;

DOI:10.1016/j.tetlet.2007.03.111

upstream raw materials:

diethyl thioglycolate

benzil

thiodiacetic acid

isopropyl chloroformate

Downstream raw materials:

2,5-dibromo-3,4-diphenylthiophene

5-bromo-3,4-diphenyl-thiophene-2-carboxylic acid

meso-3,4-diphenyl-adipic acid

3,4-diphenyl-2,5-bis(chloromethyl)thiophene