CID 14956385

Base Information

Chemical Name:CID 14956385
CAS No.:153276-73-4
Molecular Formula:C₁₂H₁₁NO₄
Molecular Weight:233.224
Hs Code.:
DSSTox Substance ID:DTXSID501235427

Synonyms:153276-73-4;DTXSID501235427;Methyl 3-formyl-7-methoxy-1H-indole-4-carboxylate

Suppliers and Price of CID 14956385

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of CID 14956385

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:233.06880783
Heavy Atom Count:17
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C2C(=C(C=C1)C(=O)OC)C(=CN2)C=O

Technology Process of CID 14956385

There total 5 articles about CID 14956385 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 153276-72-3
methyl 7-methoxy-1H-indole-4-carboxylate

: 153276-73-4
3-formyl-4-methoxycarbonyl-7-methoxyindole

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1080/00397919308013802

Reference yield:

: 3189-22-8
7-methoxy-1H-indole

: 153276-73-4
3-formyl-4-methoxycarbonyl-7-methoxyindole

Guidance literature:: Multi-step reaction with 5 steps

1: 76 percent / NaH / dimethylformamide / 0.25 h / 40 °C

2: 1.) AlCl₃ / 1.) CH₂Cl₂, from 20 deg C to 25 deg C, 30 min, 2.) reflux, 30 min

3: 96 percent / NaOH / ethanol / 3 h / Heating

4: 58 percent / HCl / 2 h / Heating

5: 80 percent / POCl₃ / dimethylformamide / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; aluminium trichloride; sodium hydride; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1080/00397919308013802

Reference yield:

: 146073-32-7
7-(methyloxy)-1-(phenylsulfonyl)-1H-indole

: 153276-73-4
3-formyl-4-methoxycarbonyl-7-methoxyindole

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) AlCl₃ / 1.) CH₂Cl₂, from 20 deg C to 25 deg C, 30 min, 2.) reflux, 30 min

2: 96 percent / NaOH / ethanol / 3 h / Heating

3: 58 percent / HCl / 2 h / Heating

4: 80 percent / POCl₃ / dimethylformamide / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; aluminium trichloride; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1080/00397919308013802