2-fluoro-3-iodoisonicotinonitrile

Base Information

Chemical Name:2-fluoro-3-iodoisonicotinonitrile
CAS No.:898854-64-3
Molecular Formula:C₆H₂FIN₂
Molecular Weight:247.998
Hs Code.:

Synonyms:

Suppliers and Price of 2-fluoro-3-iodoisonicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2-Fluoro-3-iodoisonicotinonitrile
1g
$ 3155.55

Alichem
2-Fluoro-3-iodoisonicotinonitrile
250mg
$ 931.00

Total 1 raw suppliers

Chemical Property of 2-fluoro-3-iodoisonicotinonitrile

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-3-iodoisonicotinonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-fluoro-3-iodoisonicotinonitrile

There total 2 articles about 2-fluoro-3-iodoisonicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 3939-14-8
2-fluoropyridine-4-carbonitrile

: 898854-64-3
2-fluoro-3-iodoisonicotinonitrile

Guidance literature:: 2-fluoropyridine-4-carbonitrile; With 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; In tetrahydrofuran; at -70 ℃; for 1h; Inert atmosphere;

With zinc(II) chloride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; In tetrahydrofuran; at 20 ℃; for 12h; Reagent/catalyst; regioselective reaction; Inert atmosphere;
DOI:10.1021/acs.orglett.1c02572

Reference yield:

: 19158-51-1
P-toluenesulfonyl cyanide

: 113975-22-7
2-fluoro-3-iodopyridine

: 898854-59-6
2-fluoro-4-iodonicotinonitrile

: 898854-64-3
2-fluoro-3-iodoisonicotinonitrile

Guidance literature:: 2-fluoro-3-iodopyridine; With lithium diisopropyl amide; In tetrahydrofuran; at -75 ℃; for 1.16667h;

P-toluenesulfonyl cyanide; In tetrahydrofuran; at -75 ℃; for 2h;