Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib

Base Information

Chemical Name:Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib
CAS No.:910297-71-1
Molecular Formula:C₁₆H₁₃Cl₂N₅O₂S
Molecular Weight:410.284
Hs Code.:
Mol file:910297-71-1.mol

Synonyms:

Suppliers and Price of Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloroDasatinib
10mg
$ 990.00

Medical Isotopes, Inc.
Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloroDasatinib
1 mg
$ 625.00

Total 12 raw suppliers

Chemical Property of Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib

Chemical Property:

Melting Point:237-240°C
PKA:10.69±0.70(Predicted)
Density:1.593±0.06 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloroDasatinib ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Intermediate in the preparation of Dasatinib metabolite, Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib is used in the treatment of cancers and immune diseases. Intermediate in the preparation of Dasatinib metabolite, used in the treatment of cancers and immune diseases. It is a COVID19-related research product.

Technology Process of Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib

There total 1 articles about Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro Dasatinib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 910297-70-0
3-chloro-2-(2-(6-chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamido)benzyl pivalate

: 910297-71-1
2-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-(hydroxymethyl)phenyl)thiazole-5-carboxamide

Guidance literature:: 3-chloro-2-(2-(6-chloro-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamido)benzyl pivalate; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 6h;

With hydrogenchloride; water; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h; pH=7;