ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

Base Information

• Chemical Name: ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate
• CAS No.: 1403889-24-6
• Molecular Formula: C₁₃H₁₃Cl₂N₃O₃
• Molecular Weight: 330.171
• Mol file: 1403889-24-6.mol

Synonyms:

Chemical Property of ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

There total 2 articles about ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-(3,5-dichlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (1269125-43-0) + ethyl bromoacetate (105-36-2) → ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate (1403889-24-6)

Guidance literature:

4-(3,5-dichlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one; With potassium carbonate; In acetone; at 90 ℃; for 0.0833333h; Microwave irradiation; Sealed tube;

ethyl bromoacetate; In acetone; at 90 ℃; for 0.166667h; Temperature; Time; Microwave irradiation; Sealed tube;

DOI:10.3184/174751912X13400138806685

Reference yield:

3,5-Dichloroaniline (626-43-7) → ethyl [4-(3,5-dichlorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate (1403889-24-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: neat (no solvent) / 0.17 h / 185 °C / Microwave irradiation; Sealed tube

2.1: potassium carbonate / acetone / 0.08 h / 90 °C / Microwave irradiation; Sealed tube

2.2: 0.17 h / 90 °C / Microwave irradiation; Sealed tube

With potassium carbonate; In acetone;

DOI:10.3184/174751912X13400138806685

upstream raw materials:

4-(3,5-dichlorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one

ethyl bromoacetate

3,5-Dichloroaniline