SKL 2001

Base Information

Chemical Name:SKL 2001
CAS No.:909089-13-0
Molecular Formula:C₁₄H₁₄N₄O₃
Molecular Weight:286.29
Hs Code.:
Mol file:909089-13-0.mol

Synonyms:

Suppliers and Price of SKL 2001

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
SKL2001 >98%
250 mg
$ 700.00

DC Chemicals
SKL2001 >98%
100 mg
$ 400.00

DC Chemicals
SKL2001 >98%
1 g
$ 1300.00

ChemScene
SKL2001 99.54%
100mg
$ 520.00

ChemScene
SKL2001 99.54%
200mg
$ 820.00

ChemScene
SKL2001 99.54%
50mg
$ 290.00

ChemScene
SKL2001 99.54%
10mg
$ 70.00

Cayman Chemical
SKL2001
25mg
$ 191.00

Cayman Chemical
SKL2001
10mg
$ 81.00

Cayman Chemical
SKL2001
5mg
$ 43.00

Total 14 raw suppliers

Chemical Property of SKL 2001

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

SKL2001 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description SKL2001 is an activator of Wnt/β-catenin signaling. It increases β-catenin responsive transcription in a cell-based reporter assay in a concentration-dependent manner, increases β-catenin protein levels in HEK293 cells when used at concentrations of 10 and 30 μM, and disrupts the interaction between Axin and β-catenin. SKL2001 increases alkaline phosphatase (ALP) activity and mineralization in multipotent mesenchymal ST2 cells in a concentration-dependent manner, indicating increased osteoblastogenesis. SKL2001 (40 μM) reduces HCT116 and HT-29 spheroid growth and inhibits proliferation of HCT116 and HT-29 cells. It induces cell cycle arrest at the G0/G1 phase and increases E-cadherin and β-catenin protein levels in HCT116 cells when used at a concentration of 40 μM.

Technology Process of SKL 2001

There total 1 articles about SKL 2001 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 5036-48-6
3-(1H-imidazol-1-yl)propan-1-amine

: 98434-06-1
5-(furan-2-yl)-1,2-oxazole-3-carboxylic acid

: 909089-13-0
SKL2001

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;