t-Boc-N-Amido-PEG4-Azide

Base Information

Chemical Name:t-Boc-N-Amido-PEG4-Azide
CAS No.:940951-99-5
Molecular Formula:C₁₅H₃₀N₄O₆
Molecular Weight:362.426
Hs Code.:

Synonyms:

Suppliers and Price of t-Boc-N-Amido-PEG4-Azide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
T-Boc-N-amido-PEG4-azide
100mg
$ 75.00

BroadPharm
t-Boc-N-Amido-PEG4-azide 98%
1 G
$ 400.00

BroadPharm
t-Boc-N-Amido-PEG4-azide 98%
500 MG
$ 290.00

BroadPharm
t-Boc-N-Amido-PEG4-azide 98%
2 G
$ 600.00

Apolloscientific
t-Boc-N-Amido-PEG4-Azide
500mg
$ 740.00

AK Scientific
t-Boc-N-Amido-PEG4-Azide
1g
$ 1011.00

Activate Scientific
BocNH-PEG4-CH2CH2N3 95+%
1 g
$ 489.00

Activate Scientific
BocNH-PEG4-CH2CH2N3 95+%
250 mg
$ 248.00

Acrotein
BocNH-PEG4-CH2CH2N3 97%
0.25g
$ 174.16

Total 12 raw suppliers

Chemical Property of t-Boc-N-Amido-PEG4-Azide

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

T-Boc-N-amido-PEG4-azide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description t-Boc-N-Amido-PEG4-azide is a N-Boc protected PEG reagent. It can react with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Technology Process of t-Boc-N-Amido-PEG4-Azide

There total 4 articles about t-Boc-N-Amido-PEG4-Azide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1404111-69-8
2-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate

: 940951-99-5
tert-butyl [2-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethoxy)ethyl]carbamate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 75 ℃; for 8h; Temperature; Inert atmosphere;

Reference yield:

: 84131-04-4
triethylene glycol monobenzyl tosyl ether

: 940951-99-5
tert-butyl [2-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethoxy)ethyl]carbamate

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydride / N,N-dimethyl acetamide / 10 h / 0 - 5 °C / Inert atmosphere

2: hydrogen; palladium on activated charcoal; hydrogenchloride / ethanol; water / 10 h / 50 °C

3: triethylamine; dmap / dichloromethane / 9 h / Cooling with ice

4: sodium azide / N,N-dimethyl-formamide / 8 h / 75 °C / Inert atmosphere

With hydrogenchloride; dmap; sodium azide; palladium on activated charcoal; hydrogen; sodium hydride; triethylamine; In ethanol; dichloromethane; N,N-dimethyl acetamide; water; N,N-dimethyl-formamide;

Reference yield:

: [2-(2-{2-[2-(2-benzyloxyethoxy)ethoxy]ethoxy}ethoxy)ethyl]tritylamine

: 940951-99-5
tert-butyl [2-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethoxy)ethyl]carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen; palladium on activated charcoal; hydrogenchloride / ethanol; water / 10 h / 50 °C

2: triethylamine; dmap / dichloromethane / 9 h / Cooling with ice

3: sodium azide / N,N-dimethyl-formamide / 8 h / 75 °C / Inert atmosphere

With hydrogenchloride; dmap; sodium azide; palladium on activated charcoal; hydrogen; triethylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;