tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate

Base Information

Chemical Name:tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate
CAS No.:1286272-96-5
Molecular Formula:C₁₅H₂₃N₃O₃
Molecular Weight:293.366
Hs Code.:
DSSTox Substance ID:DTXSID501130392
Mol file:1286272-96-5.mol

Synonyms:1286272-96-5;tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate;tert-butyl 4-(3-aminopyridin-2-yl)oxypiperidine-1-carboxylate;tert-butyl 4-((3-aminopyridin-2-yl)oxy)piperidine-1-carboxylate;tert-butyl 4-[(3-aminopyridin-2-yl)oxy]piperidine-1-carboxylate;SCHEMBL14335009;DTXSID501130392;AKOS026671853;KS-5732;EN300-264896;F1907-0390;tert-Butyl4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 4-[(3-amino-2-pyridinyl)oxy]-, 1,1-dimethylethyl ester

Suppliers and Price of tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate 95+%
1g
$ 431.00

Chemenu
tert-Butyl4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate 95%
1g
$ 407.00

Total 3 raw suppliers

Chemical Property of tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:293.17394160
Heavy Atom Count:21
Complexity:349

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)OC2=C(C=CC=N2)N
Uses tert-Butyl 4-(3-Aminopyridin-2-yl)oxypiperidine-1-carboxylate is used in the preparation 3-Imidazolylindoles as MDM2 and MDM4 inhibitors.

Technology Process of tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate

There total 3 articles about tert-Butyl 4-(3-aminopyridin-2-yloxy)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl 4-(3-nitropyridine-2-oxy)piperidine-1-carboxylate

: 1286272-96-5
tert-butyl 4-(3-aminopyridine-2-oxy)piperidine-1-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol;

Reference yield:

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 1286272-96-5
tert-butyl 4-(3-aminopyridine-2-oxy)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 20 °C

1.2: 20 °C

2.1: palladium 10% on activated carbon; hydrogen / methanol

With palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; methanol; mineral oil;

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 1286272-96-5
tert-butyl 4-(3-aminopyridine-2-oxy)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 20 °C

1.2: 20 °C

2.1: palladium 10% on activated carbon; hydrogen / methanol

With palladium 10% on activated carbon; hydrogen; sodium hydride; In tetrahydrofuran; methanol; mineral oil;