(R)-2-benzylsuccinic acid

Base Information

Chemical Name:(R)-2-benzylsuccinic acid
CAS No.:213681-40-4
Molecular Formula:C₈H₁₁N*C₁₁H₁₂O₄
Molecular Weight:329.396
Hs Code.:

Synonyms:

Suppliers and Price of (R)-2-benzylsuccinic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-benzylsuccinic acid

Chemical Property:

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Technology Process of (R)-2-benzylsuccinic acid

There total 1 articles about (R)-2-benzylsuccinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 36092-42-9,884-33-3
2-benzylsuccinic acid

: 2627-86-3
(S)-1-phenyl-ethylamine

: 213681-40-4
(R)-2-benzylsuccinic acid

Guidance literature:: In ethanol; at 28 - 30 ℃; for 5h; Inert atmosphere; Resolution of racemate;
DOI:10.14233/ajchem.2014.16137

Reference yield:

: 213681-40-4
(R)-2-benzylsuccinic acid

: 21307-97-1,884-33-3
(R)-2-benzylsuccinic acid

Guidance literature:: With sodium hydroxide; In dichloromethane; water; for 0.166667h; pH=13;
DOI:10.14233/ajchem.2014.16137

Reference yield:

: 213681-40-4
(R)-2-benzylsuccinic acid

: (R)-2-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / dichloromethane; water / 0.17 h / pH 13

2: acetic anhydride / dichloromethane / 3 h / 25 - 48 °C / Inert atmosphere

3: toluene / 0.5 h / 45 - 47 °C / Inert atmosphere

With acetic anhydride; sodium hydroxide; In dichloromethane; water; toluene;
DOI:10.14233/ajchem.2014.16137