Tetrahydro-2H-pyran-3-YL methanesulfonate

Base Information

Chemical Name:Tetrahydro-2H-pyran-3-YL methanesulfonate
CAS No.:129888-63-7
Molecular Formula:C₆H₁₂O₄S
Molecular Weight:180.225
Hs Code.:
DSSTox Substance ID:DTXSID30697048

Synonyms:129888-63-7;oxan-3-yl methanesulfonate;TETRAHYDRO-2H-PYRAN-3-YL METHANESULFONATE;starbld0049956;SCHEMBL707215;DTXSID30697048;methanesulfonic acid 3-oxanyl ester;tetrahydropyran-3-yl methanesulfonate;EN300-2008094;A805984

Suppliers and Price of Tetrahydro-2H-pyran-3-YL methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
Oxan-3-ylmethanesulfonate
10g
$ 3578.00

AK Scientific
Oxan-3-ylmethanesulfonate
250mg
$ 464.00

Total 3 raw suppliers

Chemical Property of Tetrahydro-2H-pyran-3-YL methanesulfonate

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:180.04563003
Heavy Atom Count:11
Complexity:203

Purity/Quality:

97% ^*data from raw suppliers

Oxan-3-ylmethanesulfonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CS(=O)(=O)OC1CCCOC1

Technology Process of Tetrahydro-2H-pyran-3-YL methanesulfonate

There total 1 articles about Tetrahydro-2H-pyran-3-YL methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 19752-84-2
Oxan-3-ol

: 124-63-0
methanesulfonyl chloride

: 129888-63-7
tetrahydro-2H-pyran-3-yl methanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 5 ℃; for 0.5h;
DOI:10.1016/0008-6215(90)84017-O

Reference yield:

: 129888-63-7
tetrahydro-2H-pyran-3-yl methanesulfonate

: 6-amino-3-chloro-2-((3-methyltetrahydro-2H-pyran-3-yl)sulfonyl)phenol

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 80 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 25 °C

3: lithium hexamethyldisilazane; trifluoroacetic acid / tetrahydrofuran / 1 h / -78 °C

4: hydrogenchloride / water; 1,4-dioxane / 12 h / 120 °C

With hydrogenchloride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 129888-63-7
tetrahydro-2H-pyran-3-yl methanesulfonate

: 6-amino-3-chloro-2-((tetrahydro-2H-pyran-3-yl)sulfonyl)phenol

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 80 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 25 °C

3: hydrogenchloride / water; 1,4-dioxane / 12 h / 120 °C

With hydrogenchloride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;