ethyl 5-amino-2-(cyanosulfanyl)benzoate

Base Information

• Chemical Name: ethyl 5-amino-2-(cyanosulfanyl)benzoate
• CAS No.: 1057669-39-2
• Molecular Formula: C₁₀H₁₀N₂O₂S
• Molecular Weight: 222.268
• Mol file: 1057669-39-2.mol

Synonyms:

Chemical Property of ethyl 5-amino-2-(cyanosulfanyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ethyl 5-amino-2-(cyanosulfanyl)benzoate

There total 2 articles about ethyl 5-amino-2-(cyanosulfanyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-aminobenzoic acid ethyl ester (582-33-2) + potassium thioacyanate (333-20-0) → 3-ethoxyformyl-4-thiocyanatoaniline (1057669-39-2)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; boron trifluoride diethyl etherate; oxygen; copper(II) bis(trifluoromethanesulfonate); In dimethyl sulfoxide; at 80 ℃; for 12h; regioselective reaction;

DOI:10.1021/acs.joc.7b01122

Reference yield:

→ 3-ethoxyformyl-4-thiocyanatoaniline (1057669-39-2)

Guidance literature:

/BRN= 3274797/;

upstream raw materials:

3-aminobenzoic acid ethyl ester

potassium thioacyanate

Refernces