t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

Base Information

Chemical Name:t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate
CAS No.:1417551-48-4
Molecular Formula:C₁₄H₁₆BrN₃O₃
Molecular Weight:354.203
Hs Code.:

Synonyms:

Suppliers and Price of t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl(4-bromo-6-methoxy-1,5-naphthyridin-3-yl)carbamate 97%
1g
$ 804.00

Chemcia Scientific
(4-Bromo-6-methoxy-[1,5]naphthyridin-3-yl)-carbamicacidtert-butylester 95%
1 G
$ 695.00

Alichem
Tert-butyl(4-bromo-6-methoxy-1,5-naphthyridin-3-yl)carbamate
1g
$ 812.00

Total 2 raw suppliers

Chemical Property of t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(4-bromo-6-methoxy-1,5-naphthyridin-3-yl)carbamate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

There total 9 articles about t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 724788-65-2
4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylic acid

: 1417551-48-4
t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

Guidance literature:: With diphenylphosphoranyl azide; triethylamine; In N,N-dimethyl-formamide; tert-butyl alcohol; at 100 ℃; for 1h;
DOI:10.1021/ml500069w

Reference yield:

: 724788-65-2
4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylic acid

: 75-65-0
tert-butyl alcohol

: 724788-66-3
4-bromo-6-(methyloxy)-1,5-naphthyridin-3-amine

: 1417551-48-4
t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

Guidance literature:: With diphenyl phosphoryl azide; triethylamine; In N,N-dimethyl-formamide; at 100 ℃; for 1h;

Reference yield:

: 6628-77-9
6-methoxy-pyridin-3-ylamine

: 1417551-48-4
t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate

Guidance literature:: Multi-step reaction with 4 steps

1: ethanol / 4 h / Reflux

2: phosphorus tribromide / N,N-dimethyl-formamide

3: sodium hydroxide / tetrahydrofuran; water / 18 h / 20 °C

4: diphenyl phosphoryl azide; triethylamine / N,N-dimethyl-formamide / 1 h / 100 °C

With diphenyl phosphoryl azide; phosphorus tribromide; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol; water; N,N-dimethyl-formamide; 4: Curtius rearrangement;
DOI:10.1016/j.bmcl.2011.09.117