2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(Z)-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)amino]acetamide

Base Information

Chemical Name:2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(Z)-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)amino]acetamide
CAS No.:70863-01-3
Molecular Formula:C18H17 N7 O4 S
Molecular Weight:427.443
Hs Code.:
NSC Number:294718

Synonyms:NSC294718;70863-01-3;NSC-294718

Suppliers and Price of 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(Z)-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)amino]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(Z)-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)amino]acetamide

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:427.10627322
Heavy Atom Count:30
Complexity:785

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)NN=C3N(C(=O)CS3)C4=CC=CC=C4
Isomeric SMILES:CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)N/N=C\3/N(C(=O)CS3)C4=CC=CC=C4

Technology Process of 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(Z)-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)amino]acetamide

There total 4 articles about 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)-N-[(Z)-(4-oxo-3-phenyl-1,3-thiazolidin-2-ylidene)amino]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 70883-30-6
1-[2-(1,3-dimethylxanthin-7-yl)acetyl]-4-(phenyl)thiosemicarbazide

: 79-04-9
chloroacetyl chloride

: 70863-01-3
2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-(phenyl)thiazolidin-4-one

Guidance literature:: In methanol; chloroform; for 10h; Reflux;
DOI:10.3390/molecules18089684

Reference yield:

: 58-55-9,75448-53-2
theophylline

: 70863-01-3
2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-(phenyl)thiazolidin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium; methanol

1.2: 7 h / Heating

2.1: hydrazine hydrate / ethanol / 6 h / Heating

3.1: 1,3-dioxane / 6 h / Reflux

4.1: methanol; chloroform / 10 h / Reflux

With methanol; sodium; hydrazine hydrate; In 1,3-dioxane; methanol; ethanol; chloroform;
DOI:10.3390/molecules18089684

Reference yield:

: 41838-25-9
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetohydrazide

: 70863-01-3
2-{2-[2-(1,3-dimethylxanthin-7-yl)acethyl]hydrazono}-3-(phenyl)thiazolidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1,3-dioxane / 6 h / Reflux

2: methanol; chloroform / 10 h / Reflux

In 1,3-dioxane; methanol; chloroform;
DOI:10.3390/molecules18089684