1-(4-Hydroxy-2,5-dimethoxyphenyl)ethan-1-one

Base Information

• Chemical Name: 1-(4-Hydroxy-2,5-dimethoxyphenyl)ethan-1-one
• CAS No.: 13909-71-2
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.203
• DSSTox Substance ID: DTXSID301271942
• Mol file: 13909-71-2.mol

Synonyms:1-(4-hydroxy-2,5-dimethoxyphenyl)ethan-1-one;13909-71-2;1-(4-hydroxy-2,5-dimethoxyphenyl)ethanone;DTXSID301271942;MFCD22378672;AKOS016354447;NS-01934;EN300-109360;Z1413438403

Chemical Property of 1-(4-Hydroxy-2,5-dimethoxyphenyl)ethan-1-one

Chemical Property:

• Melting Point: 117–118°C
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 196.07355886
• Heavy Atom Count: 14
• Complexity: 204

Purity/Quality:

99% ^*data from raw suppliers

1-(4-hydroxy-2,5-dimethoxyphenyl)ethan-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C1=CC(=C(C=C1OC)O)OC

Technology Process of 1-(4-Hydroxy-2,5-dimethoxyphenyl)ethan-1-one

There total 3 articles about 1-(4-Hydroxy-2,5-dimethoxyphenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethoxyphenol (18113-18-3) + acetic acid (64-19-7,77671-22-8) → 4-Hydroxy-2,5-dimethoxy-acetophenon (13909-71-2)

Guidance literature:

With boron trifluoride;

DOI:10.1246/bcsj.51.3612

Reference yield:

2,5-dimethoxyphenyl acetate (27257-06-3) → 4-Hydroxy-2,5-dimethoxy-acetophenon (13909-71-2)

Guidance literature:

With aluminium trichloride;

Reference yield:

→ 4-Hydroxy-2,5-dimethoxy-acetophenon (13909-71-2)

Guidance literature:

2,5-Dimethoxy-1,4-diacetoxybenzol (Ib), Eg./Polyphosphorsaeure;

DOI:10.1016/S0040-4039(00)90138-2

upstream raw materials:

2,5-dimethoxyphenyl acetate

2,5-dimethoxyphenol

acetic acid

Downstream raw materials:

4'-Hydroxy-2',5'-dimethoxychalcon

3-(2,5-Dimethoxy-4-ethyl-phenoxy)-butanon-⁽²⁾