ACETIC ACID 2,5-DIMETHOXY-PHENYL ESTER

Base Information

• Chemical Name: ACETIC ACID 2,5-DIMETHOXY-PHENYL ESTER
• CAS No.: 27257-06-3
• Molecular Formula: C10H12O4
• Molecular Weight: 196.203
• Hs Code.: 2915390090
• Mol file: 27257-06-3.mol

Synonyms:ACETIC ACID 2,5-DIMETHOXY-PHENYL ESTER

Chemical Property of ACETIC ACID 2,5-DIMETHOXY-PHENYL ESTER

Chemical Property:

• Melting Point: 63-64 °C
• Boiling Point: 265.8±25.0 °C(Predicted)
• PSA: 44.76000
• Density: 1.120±0.06 g/cm3(Predicted)
• LogP: 1.62910

Purity/Quality:

2,5-Dimethoxyphenylacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACETIC ACID 2,5-DIMETHOXY-PHENYL ESTER

There total 17 articles about ACETIC ACID 2,5-DIMETHOXY-PHENYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2',5'-dimethoxyacetophenone (1201-38-3) → 2,5-dimethoxyphenyl acetate (27257-06-3)

Guidance literature:

With dihydrogen peroxide; toluene-4-sulfonic acid;

DOI:10.1002/ejoc.201200176

Reference yield: 56.0%

[bis(acetoxy)iodo]benzene (3240-34-4) + 1,4-dimethoxybezene (150-78-7) → 2,5-dimethoxyphenyl acetate (27257-06-3)

Guidance literature:

With gold(III) chloride; In 1,2-dichloro-ethane; at 110 ℃; for 6h; regioselective reaction;

DOI:10.1021/ol202075x

Reference yield: 43.0%

trimethylsilyl acetate (2754-27-0) + 1,4-dimethoxybezene (150-78-7) → 2,5-dimethoxyphenyl acetate (27257-06-3)

Guidance literature:

With bis-[(trifluoroacetoxy)iodo]benzene; In various solvent(s); for 0.25h; Ambient temperature;

DOI:10.1021/ja00088a003

upstream raw materials:

2',5'-dimethoxyacetophenone

lead(IV) tetraacetate

acetic acid

1,4-dimethoxybezene

Downstream raw materials:

2,5-dimethoxyphenyl triflate

(4-hydroxy-2,5-dimethoxy-phenyl)-glyoxylic acid

2-(1,1-dimethylpropynyl)-5-(2-methylbut-3-yn-2-yloxy)-benzoquinone 4-dimethyl acetal

4-(2-methylbut-3-yn-2-yl)-2,5-dimethoxyphenyl 2-methylbut-3-yn-2-yl ether

Refernces

• 1、 Werner, Georg,Butenschoen, Holger. "Attempts directed towards the synthesis of intermediate (aryne)chromium complexes from aryl triflates and from (haloarene)chromium complexes". body text. p. 3132 - 3141. Retrieved 2012/06/30.
• 2、 Burasov, Alexander V.,Petrosyan, Vladimir A.. "Electrophilic components in the electrochemical acetoxylation of substituted arenes". . p. 196 - 197. Retrieved 2008/12/22.