2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

Base Information

Chemical Name:2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one
CAS No.:116212-47-6
Molecular Formula:C₈H₈N₂O
Molecular Weight:148.164
Hs Code.:
DSSTox Substance ID:DTXSID201280580
Nikkaji Number:J3.643.947E

Synonyms:2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one;SCHEMBL20586759;DTXSID201280580;116212-47-6;2-Methylpyrrolo[1,2-a]pyrazine-1(2H)-one;J3.643.947E;2-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-1-one;InChI=1/C8H8N2O/c1-9-5-6-10-4-2-3-7(10)8(9)11/h2-6H,1H

Suppliers and Price of 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2-methyl-Pyrrolo[1,2-a]pyrazin-1(2H)-one 97.00%
25G
$ 5520.00

AccelPharmtech
2-methyl-Pyrrolo[1,2-a]pyrazin-1(2H)-one 97.00%
5G
$ 2960.00

AccelPharmtech
2-methyl-Pyrrolo[1,2-a]pyrazin-1(2H)-one 97.00%
1G
$ 1740.00

Total 1 raw suppliers

Chemical Property of 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:148.063662883
Heavy Atom Count:11
Complexity:212

Purity/Quality:

95% ^*data from raw suppliers

2-methyl-Pyrrolo[1,2-a]pyrazin-1(2H)-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C=CN2C=CC=C2C1=O

Technology Process of 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one

There total 5 articles about 2-methylpyrrolo[1,2-a]pyrazin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 54993-52-1
2-methyl-3,4-dihydropyrrolo<1,2-a>pyrazin-1(2H)-one

: 116212-47-6
2-methylpyrrolo<1,2-a>pyrazin-1(2H)-one

Guidance literature:: With manganese(IV) oxide; In toluene; for 10h; Heating;

Reference yield:

: 1193-62-0
methyl Pyrrole-2-carboxylate

: 116212-47-6
2-methylpyrrolo<1,2-a>pyrazin-1(2H)-one

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) KOH / 1.) DMSO, RT, 1 h, 2.) 48 h

2: 72 percent / CoCl₂, NaBH₄ / methanol / 1 h / Ambient temperature

3: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 3 h

4: 53 percent / MnO₂ / toluene / 10 h / Heating

With manganese(IV) oxide; potassium hydroxide; sodium tetrahydroborate; sodium hydride; In methanol; toluene;

Reference yield:

: 54906-42-2
3,4-dihydropyrrolo<1,2-a>pyrazin-1(2H)-one

: 116212-47-6
2-methylpyrrolo<1,2-a>pyrazin-1(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, RT, 1 h, 2.) 3 h

2: 53 percent / MnO₂ / toluene / 10 h / Heating

With manganese(IV) oxide; sodium hydride; In toluene;