Technology Process of (11alpha,13xi)-18,21-dihydroxy-11,18-epoxypregn-4-ene-3,20-dione
There total 14 articles about (11alpha,13xi)-18,21-dihydroxy-11,18-epoxypregn-4-ene-3,20-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
air; dibutyric cyclic AMP; NaHCO3 buffer; normal male Sprague-Dawley rat adrenal glands after feeding for 72 h with 1 percent NaCl;
at 37 ℃;
for 3h;
Product distribution;
tritium labeled study;
DOI:10.1016/0039-128X(80)90082-3
- Guidance literature:
-
With
potassium dihydrogenphosphate; magnesium sulfate heptahydrate; L-asparagine; D-glucose;
In
ethanol; water;
at 30 ℃;
for 72h;
pH=5.5;
Time;
Concentration;
Overall yield = 62.95 %Chromat.;
Microbiological reaction;
DOI:10.3109/10242422.2014.894983
- Guidance literature:
-
With
potassium dihydrogenphosphate; magnesium sulfate heptahydrate; L-asparagine; D-glucose; β‐cyclodextrin;
In
ethanol; water;
at 30 ℃;
for 48h;
pH=5.5;
Solvent;
Reagent/catalyst;
Time;
Concentration;
Overall yield = 87.15 %Chromat.;
Microbiological reaction;
DOI:10.3109/10242422.2014.894983
