1-(2-Chloro-6-methylpyridin-4-YL)ethanone

Base Information

Chemical Name:1-(2-Chloro-6-methylpyridin-4-YL)ethanone
CAS No.:890406-52-7
Molecular Formula:C₈H₈ClNO
Molecular Weight:169.611
Hs Code.:
European Community (EC) Number:974-875-0

Synonyms:1-(2-CHLORO-6-METHYLPYRIDIN-4-YL)ETHANONE;890406-52-7;1-(2-CHLORO-6-METHYLPYRIDIN-4-YL)ETHAN-1-ONE;SCHEMBL4928556;NGAADBYBVYLBRT-UHFFFAOYSA-N;MFCD13188670;AKOS027339484;AB66888;AS-43428;DS-019752;EN300-1982335;A934278;A1-15932

Suppliers and Price of 1-(2-Chloro-6-methylpyridin-4-YL)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Chloro-6-methylpyridin-4-yl)ethanone 97%
1g
$ 412.00

Chemcia Scientific
1-(2-Chloro-6-methyl-pyridin-4-yl)-ethanone 95%
1 G
$ 495.00

Chemcia Scientific
1-(2-Chloro-6-methyl-pyridin-4-yl)-ethanone 95%
0.5 G
$ 330.00

AccelPharmtech
1-(2-chloro-6-methyl-4-pyridinyl)-Ethanone 97.00%
5G
$ 5270.00

AccelPharmtech
1-(2-chloro-6-methyl-4-pyridinyl)-Ethanone 97.00%
1G
$ 3060.00

A1 Biochem Labs
1-(2-Chloro-6-methylpyridin-4-yl)ethanone 95%
5 g
$ 1300.00

Total 4 raw suppliers

Chemical Property of 1-(2-Chloro-6-methylpyridin-4-YL)ethanone

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:169.0294416
Heavy Atom Count:11
Complexity:160

Purity/Quality:

98%+ ^*data from raw suppliers

1-(2-Chloro-6-methylpyridin-4-yl)ethanone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC(=N1)Cl)C(=O)C

Technology Process of 1-(2-Chloro-6-methylpyridin-4-YL)ethanone

There total 3 articles about 1-(2-Chloro-6-methylpyridin-4-YL)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 329946-08-9
2-chloro-N-methoxy-6,N-dimethylisonicotinamide

: 75-16-1
methylmagnesium bromide

: 890406-52-7
1-(2-chloro-6-methylpyridin-4-yl)ethanone

Guidance literature:: In tetrahydrofuran; at 0 ℃;

Reference yield: 79.0%

: 917-64-6
methyl magnesium iodide

: 25462-85-5
2-chloro-6-methylpyridine-4-carboxylic acid

: 890406-52-7
1-(2-chloro-6-methylpyridin-4-yl)ethanone

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 12h; Inert atmosphere;

Reference yield:

: 25462-85-5
2-chloro-6-methylpyridine-4-carboxylic acid

: 890406-52-7
1-(2-chloro-6-methylpyridin-4-yl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 2 h / 60 °C

2: tetrahydrofuran / 0 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide;