2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

Base Information

Chemical Name:2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine
CAS No.:84737-35-9
Molecular Formula:C₆H₃ClF₄N₂O
Molecular Weight:230.549
Hs Code.:

Synonyms:

Suppliers and Price of 2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine 95+%
1g
$ 880.00

Chemenu
5-chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine 95%
1g
$ 830.00

Alichem
5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine
1g
$ 771.12

Total 4 raw suppliers

Chemical Property of 2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

Chemical Property:

Boiling Point:128-130 °C(Press: 18 Torr)
Density:1.541±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

5-Chloro-2-fluoro-4-methoxy-6-(trifluoromethyl)pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

There total 3 articles about 2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 67-56-1
methanol

: 74039-20-6
2,4-difluoro-5-chloro-6-trifluoromethyl pyrimidine

: 84737-35-9
2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

Guidance literature:: With sodium carbonate; for 0.5h; Ambient temperature;
DOI:10.1016/S0022-1139(00)81461-X

Reference yield:

: 74039-25-1
6-trichloromethyl-2,4,5-trichloropyrimidine

: 84737-35-9
2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / sodium fluoride / tetrahydrothiophene 1,1-dioxide / 4 h / 200 °C

2: 65 percent / antimony trifluoride, antimony pentachloride / 1.5 h / 135 °C

3: 52 percent / Na₂CO₃ / 0.5 h / Ambient temperature

With antimonypentachloride; antimony(III) fluoride; sodium carbonate; sodium fluoride; In sulfolane;
DOI:10.1016/S0022-1139(00)81461-X

Reference yield:

: 84372-18-9
5-Chloro-2,4-difluoro-6-trichloromethyl-pyrimidine

: 84737-35-9
2-fluoro-4-methoxy-5-chloro-6-trifluoromethyl pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / antimony trifluoride, antimony pentachloride / 1.5 h / 135 °C

2: 52 percent / Na₂CO₃ / 0.5 h / Ambient temperature

With antimonypentachloride; antimony(III) fluoride; sodium carbonate;
DOI:10.1016/S0022-1139(00)81461-X