5-bromo-N'-[(E)-(4-chlorophenyl)methylidene]-2-hydroxybenzohydrazide

Base Information

• Chemical Name: 5-bromo-N'-[(E)-(4-chlorophenyl)methylidene]-2-hydroxybenzohydrazide
• CAS No.: 302909-34-8
• Molecular Formula: C₁₄H₁₀BrClN₂O₂
• Molecular Weight: 353.603
• European Community (EC) Number: 657-174-1

Synonyms:5-bromo-N'-[(E)-(4-chlorophenyl)methylidene]-2-hydroxybenzohydrazide;STK054024;AKOS005386336;SR-01000210469;SR-01000210469-1;5-Bromo-N'-(4-chlorobenzylidene)-2-hydroxybenzohydrazide

Chemical Property of 5-bromo-N'-[(E)-(4-chlorophenyl)methylidene]-2-hydroxybenzohydrazide

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 351.96142
• Heavy Atom Count: 20
• Complexity: 359

Purity/Quality:

97% ^*data from raw suppliers

5-BROMO-N'-(4-CHLOROBENZYLIDENE)-2-HYDROXYBENZOHYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1C=NNC(=O)C2=C(C=CC(=C2)Br)O)Cl
• Isomeric SMILES: C1=CC(=CC=C1/C=N/NC(=O)C2=C(C=CC(=C2)Br)O)Cl

Technology Process of 5-bromo-N'-[(E)-(4-chlorophenyl)methylidene]-2-hydroxybenzohydrazide

There total 2 articles about 5-bromo-N'-[(E)-(4-chlorophenyl)methylidene]-2-hydroxybenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-2-hydroxy-benzoic acid methyl ester (4068-76-2) → 5-bromo-2-hydroxy-benzoic acid-(4-chloro-benzylidenehydrazide) (302909-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄+H₂O

With hydrazine hydrate;

Reference yield:

2-hydroxy-5-bromobenzohydrazide (39635-10-4) + 4-chlorobenzaldehyde (104-88-1) → 5-bromo-2-hydroxy-benzoic acid-(4-chloro-benzylidenehydrazide) (302909-34-8)

Guidance literature:

upstream raw materials:

2-hydroxy-5-bromobenzohydrazide

4-chlorobenzaldehyde

5-bromo-2-hydroxy-benzoic acid methyl ester

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