tetrabutylammonium pyrophosphate

Base Information

• Chemical Name: tetrabutylammonium pyrophosphate
• CAS No.: 857447-79-1
• Molecular Formula: 2C₁₆H₃₆N*H₂O₇P₂
• Molecular Weight: 660.896
• Mol file: 857447-79-1.mol

Synonyms:

Chemical Property of tetrabutylammonium pyrophosphate

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(tetrabutylammonium) Dihydrogen Pyrophosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetrabutylammonium pyrophosphate

There total 2 articles about tetrabutylammonium pyrophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

tetra(n-butyl)ammonium hydroxide (2052-49-5) → tetrabutylammonium pyrophosphate (857447-79-1)

Guidance literature:

With tetrasodium pyrophosphate decahydrate; In water; pH=3.5;

DOI:10.1002/chem.201502844

Reference yield: 57.0%

tetrabutylammonium dihydrogen phosphate (5574-97-0) → tetrabutylammonium pyrophosphate (857447-79-1)

Guidance literature:

With Tri-n-octylamine; benzenesulfenyl chloride; In tetrahydrofuran; acetonitrile; at 20 ℃; pH=6;

DOI:10.1002/1099-0690(200109)2001:18<3457::AID-EJOC3457<3.0.CO;2-C

Reference yield:

5-chloro-cycloSal-N2-formamidine-8-N-acetyl-N-3,5-dimethylphenyl-2'-deoxyguanosine-5'-monophosphate + tetrabutylammonium pyrophosphate (857447-79-1) → C23H29N7O14P3(3-)*2C16H36N(1+)*H(1+)

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere; Molecular sieve;

DOI:10.1002/cbic.201500293

upstream raw materials:

tetrabutylammonium dihydrogen phosphate

tetra(n-butyl)ammonium hydroxide

Refernces

• 1、 Sarac, Ivo,Meier, Chris. "Efficient Automated Solid-Phase Synthesis of DNA and RNA 5′-Triphosphates". supporting information. p. 16421 - 16426. Retrieved 2015/11/09.
• 2、 Pasquato, Lucia,Santoni, Gabriella,Modena, Giorgio. ""RS+" as a coupling reagent for phosphorylation and carboxylic acid activation". . p. 3457 - 3460. Retrieved 2007/10/03.