(1S,2S)-2-iodocyclopropanecarboxylic acid

Base Information

• Chemical Name: (1S,2S)-2-iodocyclopropanecarboxylic acid
• CAS No.: 1932315-23-5
• Molecular Formula: C₄H₅IO₂
• Molecular Weight: 211.987
• Mol file: 1932315-23-5.mol

Synonyms:

Chemical Property of (1S,2S)-2-iodocyclopropanecarboxylic acid

Chemical Property:

• Boiling Point: 293.9±33.0 °C(Predicted)
• Density: 2.30±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

(1S,2S)-2-iodocyclopropanecarboxylicacid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,2S)-2-iodocyclopropanecarboxylic acid

There total 8 articles about (1S,2S)-2-iodocyclopropanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(±)-(cis)-2-iodocyclopropyl-N,N-diethylcarboxamide (467426-68-2) → (±)-(cis)-2-iodocyclopropanecarboxylic acid (122676-92-0,692288-05-4,1932315-23-5)

Guidance literature:

With sulfuric acid; In acetic acid; for 240h; Reflux;

DOI:10.1021/acs.joc.7b00945

Reference yield: 98.0%

C4H5IO2*C15H17N → (1R,2R)-2-iodocyclopropanecarboxylic acid (692288-05-4,1932315-23-5)

Guidance literature:

C₄H₅IO₂*C₁₅H₁₇N; With sodium hydroxide; In dichloromethane; for 0.0833333h;

With hydrogenchloride; Acidic conditions;

DOI:10.1021/op0341871

Reference yield: 81.0%

((1S*,2S*)-2-iodocyclopropyl)methanol → (1S*,2S*)-2-iodocyclopropanecarboxylic acid (692288-05-4,1932315-23-5)

Guidance literature:

With Jones reagent; In acetone; at 20 ℃;

DOI:10.1021/ol1029996

upstream raw materials:

cis-1-(Hydroxymethyl)-2-iodocyclopropane

4,5-Methano-1-hydroxyiodoxol-3(1H)-one

(±)-(cis)-2-iodocyclopropyl-N,N-diethylcarboxamide

(±)-(cis)-2-iodocyclopropanecarboxylic acid