C₁₂H₁₇NO₂

Base Information

• Chemical Name: C₁₂H₁₇NO₂
• CAS No.: 1391434-02-8
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.272
• Mol file: 1391434-02-8.mol

Synonyms:

Chemical Property of C₁₂H₁₇NO₂

Chemical Property:

• Boiling Point: 350.5±32.0 °C(Predicted)
• PKA: 14.93±0.10(Predicted)
• Density: 1.082±0.06 g/cm3(Predicted)

Purity/Quality:

((2R,3R)-2-(4-METHOXYPHENYL)PYRROLIDIN-3-YL)METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₂H₁₇NO₂

There total 2 articles about C₁₂H₁₇NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H10N2O → C12H17NO2 (1391434-02-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: silver(I) acetate; caesium carbonate / toluene / 0 - 20 °C / Inert atmosphere

2.1: borane-THF / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere

2.2: 3 h / 0 °C / Inert atmosphere

2.3: Inert atmosphere

With borane-THF; silver(I) acetate; caesium carbonate; In tetrahydrofuran; toluene;

DOI:10.1016/j.tetlet.2016.11.035

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → C12H17NO2 (1391434-02-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / ethanol / 0.5 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: silver(I) acetate; caesium carbonate / toluene / 0 - 20 °C / Inert atmosphere

3.1: borane-THF / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere

3.2: 3 h / 0 °C / Inert atmosphere

3.3: Inert atmosphere

With borane-THF; silver(I) acetate; caesium carbonate; triethylamine; In tetrahydrofuran; ethanol; toluene;

DOI:10.1016/j.tetlet.2016.11.035

upstream raw materials:

4-methoxy-benzaldehyde