Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Base Information

• Chemical Name: Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester
• CAS No.: 189624-76-8
• Molecular Formula: C₃₅H₄₉NO₂
• Molecular Weight: 515.78
• Mol file: 189624-76-8.mol

Synonyms:

Chemical Property of Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

There total 2 articles about Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7α-bromocholest-5-en-3β-ol benzoate (26048-46-4) + potassium cyanide (151-50-8) → Benzoic acid (3S,7S,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (189624-75-7) + Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (189624-76-8)

Guidance literature:

In dimethyl sulfoxide; at 90 ℃; for 20h; Yield given. Yields of byproduct given;

DOI:10.1080/00397919708006797

Reference yield:

7α-bromocholest-5-en-3β-ol benzoate (26048-46-4) + tetra-n-butylammonium cyanide (10442-39-4) → Benzoic acid (3S,7S,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (189624-75-7) + Benzoic acid (3S,7R,8S,9S,10R,13R,14S,17R)-7-cyano-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester (189624-76-8)

Guidance literature:

In dichloromethane; for 12h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1080/00397919708006797

upstream raw materials:

7α-bromocholest-5-en-3β-ol benzoate

tetra-n-butylammonium cyanide

potassium cyanide