2,4,5-Tris(4-methoxyphenyl)-1H-imidazole

Base Information

• Chemical Name: 2,4,5-Tris(4-methoxyphenyl)-1H-imidazole
• CAS No.: 1728-96-7
• Molecular Formula: C24H22 N2 O3
• Molecular Weight: 386.45
• DSSTox Substance ID: DTXSID80169402
• Nikkaji Number: J900.602H
• Wikidata: Q83039079
• ChEMBL ID: CHEMBL1554930
• Mol file: 1728-96-7.mol

Synonyms:2,4,5-Tris(4-methoxyphenyl)-1H-imidazole;CCRIS 8674;1728-96-7;1H-Imidazole, 2,4,5-tris(4-methoxyphenyl)-;SR-03000000712-1;Oprea1_747322;Oprea1_843600;SCHEMBL8008805;CHEMBL1554930;BDBM67491;cid_1076653;DTXSID80169402;2,4,5-Tri(4-methoxyphenyl)-1H-imidazole;LS-188248

Chemical Property of 2,4,5-Tris(4-methoxyphenyl)-1H-imidazole

Chemical Property:

• Vapor Pressure: 3E-13mmHg at 25°C
• Boiling Point: 589.4°C at 760 mmHg
• Flash Point: 204.8°C
• Density: 1.175g/cm³
• XLogP3: 5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 386.16304257
• Heavy Atom Count: 29
• Complexity: 481

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC

Technology Process of 2,4,5-Tris(4-methoxyphenyl)-1H-imidazole

There total 14 articles about 2,4,5-Tris(4-methoxyphenyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-methoxybenzonitrile (874-90-8) → 2,4,5-tris(4-methoxyphenyl)-1H-imidazole (1728-96-7)

Guidance literature:

With [(bis(diisopropylphosphino)ethane)Ni(H)]2; hydrogen; at 180 ℃; for 48h; under 6205.94 Torr; neat (no solvent);

DOI:10.1039/c1cc13497c

Reference yield: 95.0%

4-methoxy-benzaldehyde (123-11-5) + 1,2-bis(4-methoxyphenyl)-1,2-ethanedione (1226-42-2) → 2,4,5-tris(4-methoxyphenyl)-1H-imidazole (1728-96-7)

Guidance literature:

With ammonium acetate; In ethanol; at 40 ℃; for 0.583333h; Sonication; Green chemistry;

DOI:10.1016/j.ultsonch.2012.10.004

Reference yield: 89.0%

→ 2,4,5-tris(4-methoxyphenyl)-1H-imidazole (1728-96-7)

Guidance literature:

With zinc indium sulphide; In acetonitrile; for 24h; Inert atmosphere; Sealed tube; Irradiation;

upstream raw materials:

ammonium acetate

4-methoxy-benzaldehyde

1,2-bis(4-methoxyphenyl)-1,2-ethanedione

(p-methoxyphenyl)nitromethane