Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

Base Information

Chemical Name:Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate
CAS No.:140893-10-3
Molecular Formula:C12H16O4
Molecular Weight:224.257
Hs Code.:
DSSTox Substance ID:DTXSID90472353
Wikidata:Q82301241
Mol file:140893-10-3.mol

Synonyms:Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate;140893-10-3;SCHEMBL6375038;DTXSID90472353;QVFAFFSUDCLVCA-UHFFFAOYSA-N;FT-0735380;ethyl 2-[4-(2-hydroxyethyl)-phenoxy]acetate

Suppliers and Price of Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:224.10485899
Heavy Atom Count:16
Complexity:197

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)COC1=CC=C(C=C1)CCO

Technology Process of Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

There total 1 articles about Ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 501-94-0
p-hydroxyphenethyl alcohol

: 105-36-2
ethyl bromoacetate

: 140893-10-3
ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

Guidance literature:: With potassium carbonate; sodium iodide; In acetone; for 10h; Heating;
DOI:10.1248/cpb.42.521

Reference yield:

: 124-63-0
methanesulfonyl chloride

: 67-63-0,8013-70-5
isopropyl alcohol

: 140893-10-3
ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

: ethyl 2-[4-(2-methanesulfonyloxyethyl)phenoxy]acetate

Guidance literature:: With triethylamine; In water; ethyl acetate;

Reference yield:

: 140893-10-3
ethyl 2-[4-(2-hydroxyethyl)phenoxy]acetate

: {4-[2-(2-Benzenesulfonylamino-ethylsulfanyl)-ethyl]-phenoxy}-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 16 h / Ambient temperature

2: triethylamine / ethanol / 16 h / Ambient temperature

3: sodium hydroxide / ethanol / 2 h / Ambient temperature

With sodium hydroxide; triethylamine; In ethanol; dichloromethane;
DOI:10.1016/0223-5234(94)90036-1