Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat

Base Information

• Chemical Name: Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat
• CAS No.: 84763-35-9
• Molecular Formula: C₁₄H₂₀O₇
• Molecular Weight: 300.309
• Mol file: 84763-35-9.mol

Synonyms:

Chemical Property of Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat

There total 3 articles about Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohexenone (930-68-7) + trimethyl ethane-1,1,2-tricarboxylate (40967-67-7) → Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat (84763-35-9)

Guidance literature:

With ethanol; sodium; at 35 ℃; for 3h; Yield given;

Reference yield:

malonic acid dimethyl ester (108-59-8) → Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat (84763-35-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / NaOMe

2: 1) Mg/MeOH / 1) 5 deg C, 30 min, 2) room temp., 1 h; reflux, 1 h

With methanol; sodium methylate; magnesium;

Reference yield:

cyclohexenone (930-68-7) + trimethyl ethane-1,1,2-tricarboxylate (40967-67-7) → Dimethyl-2,9-dioxobicyclo<4.3.0>nonan-7,7-dicarboxylat + Trimethyl-1-(3-oxocyclohexyl)-1,1,2-ethantricarboxylat (84763-35-9)

Guidance literature:

With methanol; magnesium; Yield given. Multistep reaction. Yields of byproduct given; 1) 5 deg C, 30 min, 2) room temp., 1 h; reflux, 1 h;

upstream raw materials:

cyclohexenone

trimethyl ethane-1,1,2-tricarboxylate

malonic acid dimethyl ester

Refernces