(S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol

Base Information

Chemical Name:(S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol
CAS No.:141113-37-3
Molecular Formula:C9H8F2O2
Molecular Weight:186.15500
Hs Code.:
DSSTox Substance ID:DTXSID801254749
Nikkaji Number:J1.504.800J
Mol file:141113-37-3.mol

Synonyms:141113-37-3;(S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol;SCHEMBL7862053;WUSWCTQDBNDGFD-VIFPVBQESA-N;DTXSID801254749;(2S)-2-(2,4-Difluorophenyl)-2-oxiranemethanol;(2S)-2-(2,4-Difluorophenyl)oxirane-2beta-methanol

Suppliers and Price of (S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol

Chemical Property:

PSA：32.76000
LogP:1.18260
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:186.04923582
Heavy Atom Count:13
Complexity:200

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(O1)(CO)C2=C(C=C(C=C2)F)F
Isomeric SMILES:C1[C@@](O1)(CO)C2=C(C=C(C=C2)F)F

Technology Process of (S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol

There total 8 articles about (S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 173837-73-5
(S)-2-(2,4-difluorophenyl)-1-isobutyryloxy-3-methanesulfonyloxy-2-propanol

: 141113-37-3
(S)-(2-(2,4-difluorophenyl)oxiran-2-yl)methanol

Guidance literature:: With potassium hydroxide; In toluene; at 20 ℃;
DOI:10.1016/S0040-4039(01)00425-7

Reference yield:

: 173837-63-3
(S)-2-(2,4-difluorophenyl)-1-acetoxy-3-methanesulfonyloxy-2-propanol

: 141113-37-3
(S)-(2-(2,4-difluorophenyl)oxiran-2-yl)methanol

Guidance literature:: With potassium hydroxide; In toluene;

Reference yield:

: 141113-36-2
2-(2,4-difluorophenyl)allyl alcohol

: 141113-37-3
(S)-(2-(2,4-difluorophenyl)oxiran-2-yl)methanol

: 141113-39-5
(S)-(2-(2,4-difluorophenyl)oxiran-2-yl)methanol

Guidance literature:: With titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; In n-heptane; dichloromethane; at -20 ℃; for 8h; Overall yield = 44 %; Overall yield = 4.7 g; Inert atmosphere;
DOI:10.1002/cjoc.201300430