2-(2,4-Difluorophenyl)prop-2-en-1-ol

Base Information

Chemical Name:2-(2,4-Difluorophenyl)prop-2-en-1-ol
CAS No.:141113-36-2
Molecular Formula:C9H8F2O
Molecular Weight:170.159
Hs Code.:
DSSTox Substance ID:DTXSID70450795
Wikidata:Q72464007
Mol file:141113-36-2.mol

Synonyms:2-(2,4-difluorophenyl)prop-2-en-1-ol;141113-36-2;2-(2,4-Difluorophenyl)-2-propen-1-ol;2-(2,4-Difluoro-phenyl)-prop-2-en-1-ol;SCHEMBL6945770;DTXSID70450795;AKOS015951210;SB33357;AS-77843;Benzeneethanol, 2,4-difluoro-ss-methylene-;CS-0158061;FT-0666816;Benzeneethanol, 2,4-difluoro-beta-methylene-;D94514

Suppliers and Price of 2-(2,4-Difluorophenyl)prop-2-en-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2,4-Difluorophenyl)-2-propen-1-ol
100 mg
$ 130.00

J&W Pharmlab
2-(2,4-Difluoro-phenyl)-prop-2-en-1-ol 96%
1g
$ 350.00

J&W Pharmlab
2-(2,4-Difluoro-phenyl)-prop-2-en-1-ol 96%
500mg
$ 225.00

J&W Pharmlab
2-(2,4-Difluoro-phenyl)-prop-2-en-1-ol 96%
5g
$ 980.00

Crysdot
2-(2,4-Difluorophenyl)prop-2-en-1-ol 95+%
1g
$ 772.00

Biosynth Carbosynth
2-(2,4-Difluorophenyl)-2-propen-1-ol
50 mg
$ 120.50

Biosynth Carbosynth
2-(2,4-Difluorophenyl)-2-propen-1-ol
100 mg
$ 219.00

Biosynth Carbosynth
2-(2,4-Difluorophenyl)-2-propen-1-ol
250 mg
$ 397.50

Biosynth Carbosynth
2-(2,4-Difluorophenyl)-2-propen-1-ol
500 mg
$ 720.00

Biosynth Carbosynth
2-(2,4-Difluorophenyl)-2-propen-1-ol
1 g
$ 1310.40

Total 8 raw suppliers

Chemical Property of 2-(2,4-Difluorophenyl)prop-2-en-1-ol

Chemical Property:

Boiling Point:229℃
PKA:14.07±0.10(Predicted)
Flash Point:92℃
PSA：20.23000
Density:1.205
LogP:1.97030
Solubility.:Dichloromethane, Ether, Ethyl Acetate, Methanol
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:170.05432120
Heavy Atom Count:12
Complexity:170

Purity/Quality:

95% ^*data from raw suppliers

2-(2,4-Difluorophenyl)-2-propen-1-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C(CO)C1=C(C=C(C=C1)F)F
Uses Intermediate in the preparation of antifungal agents.

Technology Process of 2-(2,4-Difluorophenyl)prop-2-en-1-ol

There total 5 articles about 2-(2,4-Difluorophenyl)prop-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 164347-62-0
1,2-epoxy-3-chloro-2-(2,4-difluorophenyl)-propane

: 141113-36-2
2-(2,4-difluorophenyl)allyl alcohol

Guidance literature:: With sodium hydroxymethanesulfinate dihydrate; sodium hydroxide; In 1,4-dioxane; at 55 - 60 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/cjoc.201300430

Reference yield:

: 149809-34-7
1-[2-(2,4-Difluorophenyl)]-2-propenol Acetate

: 60-29-7,927820-24-4
diethyl ether

: 7440-44-0
pyrographite

: 141113-36-2
2-(2,4-difluorophenyl)allyl alcohol

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; water;

Reference yield:

: 86386-74-5
1,3-(dichloro)-2-(2,4-difluorophenyl)propan-2-ol

: 141113-36-2
2-(2,4-difluorophenyl)allyl alcohol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

2: sodium hydroxymethanesulfinate dihydrate; sodium hydroxide / 1,4-dioxane / 0.5 h / 55 - 60 °C / Inert atmosphere

With sodium hydroxymethanesulfinate dihydrate; sodium hydride; sodium hydroxide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1002/cjoc.201300430