4-(3-Methoxyphenyl)azetidin-2-one

Base Information

Chemical Name:4-(3-Methoxyphenyl)azetidin-2-one
CAS No.:83716-64-7
Molecular Formula:C₁₀H₁₁NO₂
Molecular Weight:177.203
Hs Code.:
DSSTox Substance ID:DTXSID601299066
Nikkaji Number:J801.517A

Synonyms:4-(3-Methoxyphenyl)-2-azetidinone;4-(3-methoxyphenyl)azetidin-2-one;83716-64-7;RARECHEM AL CA 0016;DTXSID601299066;AKOS006292028;CS-0349367;EN300-622286;F79407

Suppliers and Price of 4-(3-Methoxyphenyl)azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-(3-Methoxyphenyl)azetidin-2-one

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:205

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2CC(=O)N2

Technology Process of 4-(3-Methoxyphenyl)azetidin-2-one

There total 3 articles about 4-(3-Methoxyphenyl)azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 591-31-1
3-methoxy-benzaldehyde

: 83716-64-7
4-(3-methoxy-phenyl)-azetidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) diethyl ether, hexane, 4 h, room temp., 2.) 12 h, reflux

2: 2.) NaHCO₃ / 1.) diethyl ether, 2.) H₂O, ether, room temp.

With n-butyllithium; sodium hydrogencarbonate;
DOI:10.1055/s-1982-29893

Reference yield:

: 626-20-0
3-methoxystyrene

: 1189-71-5
isocyanate de chlorosulfonyle

: 83716-64-7
4-(3-methoxy-phenyl)-azetidin-2-one

: 83716-67-0
(E)-3-(3-methoxyphenyl)acrylamide

Guidance literature:: With sodium hydrogencarbonate; Yield given. Multistep reaction. Yields of byproduct given; 1.) diethyl ether, 2.) H₂O, ether, room temp.;
DOI:10.1055/s-1982-29893