Lys-Leu-Thr-Trp-Met-Glu-Leu-Tir-Gln-Leu-Ala-Tyr-Lis-Gly-Ile

Base Information

• Chemical Name: Lys-Leu-Thr-Trp-Met-Glu-Leu-Tir-Gln-Leu-Ala-Tyr-Lis-Gly-Ile
• CAS No.: 701977-50-6
• Molecular Formula: C₉₁H₁₄₀N₂₀O₂₂S
• Molecular Weight: 1898.3
• Mol file: 701977-50-6.mol

Synonyms:

Chemical Property of Lys-Leu-Thr-Trp-Met-Glu-Leu-Tir-Gln-Leu-Ala-Tyr-Lis-Gly-Ile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Lys-Leu-Thr-Trp-Met-Glu-Leu-Tir-Gln-Leu-Ala-Tyr-Lis-Gly-Ile

There total 1 articles about Lys-Leu-Thr-Trp-Met-Glu-Leu-Tir-Gln-Leu-Ala-Tyr-Lis-Gly-Ile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Leu-OH (35661-60-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) + Fmoc-Glu(OtBu)-OH (71989-18-9) + acetic anhydride (108-24-7) + Fmoc-Ile-OH (71989-23-6,251316-98-0) + Fmoc-Trp-OH (35737-15-6) + Fmoc-Tyr(tBu)-OH (71989-38-3,118488-18-9,204384-67-8) + Fmoc-Thr(tBu)-OH (71989-35-0,138797-71-4) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine (71989-28-1) → Lys-Leu-Thr-Trp-Met-Glu-Leu-Tir-Gln-Leu-Ala-Tyr-Lis-Gly-Ile (701977-50-6)

Guidance literature:

Fmoc-Ile-OH; With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.75h; Rink amide MBHA resin

With piperidine; In N,N-dimethyl-formamide; for 0.166667h; Rink amide MBHA resin

N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Glu(OtBu)-OH; acetic anhydride; Fmoc-Trp-OH; Fmoc-Tyr(tBu)-OH; Fmoc-Thr(tBu)-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine; Fmoc-L-Lys(PG)-OH, PG = protecting group; Fmoc-L-Gln(PG)-OH, PG = protecting group; Further stages;

DOI:10.1002/psc.2480

upstream raw materials:

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Leu-OH

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Fmoc-Glu(OtBu)-OH