7-ethoxy-6-methoxy-4-phenyl-coumarin

Base Information

• Chemical Name: 7-ethoxy-6-methoxy-4-phenyl-coumarin
• CAS No.: 107683-56-7
• Molecular Formula: C₁₈H₁₆O₄
• Molecular Weight: 296.323
• Mol file: 107683-56-7.mol

Synonyms:

Chemical Property of 7-ethoxy-6-methoxy-4-phenyl-coumarin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-ethoxy-6-methoxy-4-phenyl-coumarin

There total 7 articles about 7-ethoxy-6-methoxy-4-phenyl-coumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-hydroxy-4-phenylcoumarin (2555-30-8) → 7-ethoxy-6-methoxy-4-phenyl-coumarin (107683-56-7)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate; acetone

2: aq. NaOH solution; potassium peroxo disulfate / anschliessend erwaermen mit Natriumsulfit und wss. Salzsaeure

3: potassium carbonate; acetone

With sodium hydroxide; dipotassium peroxodisulfate; potassium carbonate; acetone;

Reference yield:

7-ethoxy-4-phenyl-2H-chromen-2-one (108979-94-8) → 7-ethoxy-6-methoxy-4-phenyl-coumarin (107683-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH solution; potassium peroxo disulfate / anschliessend erwaermen mit Natriumsulfit und wss. Salzsaeure

2: potassium carbonate; acetone

With sodium hydroxide; dipotassium peroxodisulfate; potassium carbonate; acetone;

Reference yield:

7-(benzyloxy)-4-phenyl-2H-chromen-2-one (110876-08-9) → 7-ethoxy-6-methoxy-4-phenyl-coumarin (107683-56-7)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. NaOH solution; potassium peroxo disulfate / anschliessend erwaermen mit Natriumsulfit und wss. Salzsaeure

2: potassium carbonate; acetone

3: concentrated aqueous hydrochloric acid; acetic acid

4: potassium carbonate; acetone

With hydrogenchloride; sodium hydroxide; dipotassium peroxodisulfate; potassium carbonate; acetic acid; acetone;

upstream raw materials:

diethyl sulfate

4-phenyl-6-methoxy-7-hydroxycoumarin

7-ethoxy-6-hydroxy-4-phenyl-coumarin

dimethyl sulfate