Methanone, [(1R,2S,4R,5S)-2-hydroxy-4,5-bis(4-methoxyphenyl)-2-phenylcyclopent yl]phenyl-, rel-

Base Information

• Chemical Name: Methanone, [(1R,2S,4R,5S)-2-hydroxy-4,5-bis(4-methoxyphenyl)-2-phenylcyclopent yl]phenyl-, rel-
• CAS No.: 141553-68-6
• Molecular Formula: C₃₂H₃₀O₄
• Molecular Weight: 478.588
• Mol file: 141553-68-6.mol

Synonyms:

Chemical Property of Methanone, [(1R,2S,4R,5S)-2-hydroxy-4,5-bis(4-methoxyphenyl)-2-phenylcyclopent yl]phenyl-, rel-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanone, [(1R,2S,4R,5S)-2-hydroxy-4,5-bis(4-methoxyphenyl)-2-phenylcyclopent yl]phenyl-, rel-

There total 9 articles about Methanone, [(1R,2S,4R,5S)-2-hydroxy-4,5-bis(4-methoxyphenyl)-2-phenylcyclopent yl]phenyl-, rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one (959-33-1) → 1,2-cis-2,3-trans-3,4-trans-2-benzoyl-1-phenyl-3,4-di(4-methoxyphenyl)cyclopentanol (84627-13-4,111612-24-9,111612-25-0,141553-68-6)

Guidance literature:

With samarium; titanium tetrachloride; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield: 67.0%

trans-4-methoxychalcone (22252-15-9) → 3-(4-methoxyphenyl)-1-phenylpropan-1-one (1669-49-4) + 1,2-cis-2,3-trans-3,4-trans-2-benzoyl-1-phenyl-3,4-di(4-methoxyphenyl)cyclopentanol (84627-13-4,111612-24-9,111612-25-0,141553-68-6)

Guidance literature:

With ammonium chloride; zinc; In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1071/CH07120

Reference yield: 55.0%

trans-4-methoxychalcone (22252-15-9) → 1,2-cis-2,3-trans-3,4-trans-2-benzoyl-1-phenyl-3,4-di(4-methoxyphenyl)cyclopentanol (84627-13-4,111612-24-9,111612-25-0,141553-68-6)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; for 0.0833333h; Ambient temperature;

upstream raw materials:

trans-4-methoxychalcone

benzaldehyde

4-methoxy-benzaldehyde

3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one