3-(4-METHOXYPHENYL)PROPIOPHENONE

Base Information

• Chemical Name: 3-(4-METHOXYPHENYL)PROPIOPHENONE
• CAS No.: 1669-49-4
• Molecular Formula: C16H16 O2
• Molecular Weight: 240.302
• Mol file: 1669-49-4.mol

Synonyms:Propiophenone,3-(p-methoxyphenyl)- (6CI,7CI,8CI); 1-Phenyl-3-(p-methoxyphenyl)-1-propanone;2-[(4-Methoxyphenyl)ethyl] phenyl ketone;3-(4-Methoxyphenyl)-1-phenylpropan-1-one; 3-(p-Methoxyphenyl)propiophenone; NSC55911

Chemical Property of 3-(4-METHOXYPHENYL)PROPIOPHENONE

Chemical Property:

• Vapor Pressure: 2.36E-06mmHg at 25°C
• Boiling Point: 392°Cat760mmHg
• Flash Point: 175.1°C
• PSA: 26.30000
• Density: 1.081g/cm³
• LogP: 3.51070

Purity/Quality:

99% ^*data from raw suppliers

3-(4-methoxyphenyl)propiophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(4-METHOXYPHENYL)PROPIOPHENONE

There total 86 articles about 3-(4-METHOXYPHENYL)PROPIOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one (959-33-1) → 3-(4-methoxyphenyl)-1-phenylpropan-1-one (1669-49-4)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; malononitrile; In dichloromethane; at 20 ℃; for 15h; regioselective reaction;

DOI:10.1002/ejoc.201200020

Reference yield: 98.0%

1-Phenylethanol (98-85-1,13323-81-4) + 4-Methoxybenzyl alcohol (105-13-5) → 3-(4-methoxyphenyl)-1-phenylpropan-1-one (1669-49-4)

Guidance literature:

With C₃₈H₄₃ClIrN₂O₂P; caesium carbonate; silver(I) triflimide; In toluene; at 120 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1021/cs5009909

Reference yield: 98.0%

acetophenone (98-86-2) + 4-Methoxybenzyl alcohol (105-13-5) → 3-(4-methoxyphenyl)-1-phenylpropan-1-one (1669-49-4)

Guidance literature:

With C₃₈H₄₃IrN₂PS₂⁽¹⁺⁾*CF₃O₃S^(1-); caesium carbonate; In tert-Amyl alcohol; at 120 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.11.034

upstream raw materials:

p-methylanizole

α-methoxystyrene

acetophenone

4-Methoxybenzyl alcohol

Downstream raw materials:

4-(3-phenyl-but-2-enyl)-anisole

3-(4-methoxyphenyl)-1-phenylpropan-1-ol

3-(4-methoxyphenyl)-2-phenyl-2-hydroxypropanoic

2,2-diazido-3-(4-methoxyphenyl)-1-phenylpropan-1-one