1-(Thiophene-2-carbonyl)piperidin-4-one

Base Information

Chemical Name:1-(Thiophene-2-carbonyl)piperidin-4-one
CAS No.:141945-71-3
Molecular Formula:C10H11NO2S
Molecular Weight:209.269
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80565849
Wikidata:Q82451153
Mol file:141945-71-3.mol

Synonyms:141945-71-3;1-(thien-2-ylcarbonyl)piperidin-4-one;1-(thiophene-2-carbonyl)piperidin-4-one;1-(2-thienylcarbonyl)-4-piperidinone;4-Piperidinone, 1-(2-thienylcarbonyl)-;1-(Thiophene-2-carbonyl)-piperidin-4-one;SCHEMBL642316;DTXSID80565849;REOJKSKCKNLFCW-UHFFFAOYSA-N;AKOS000185062;CCG-138928;SB44049;LS-01360;CS-0320944

Suppliers and Price of 1-(Thiophene-2-carbonyl)piperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(Thien-2-ylcarbonyl)piperidin-4-one
500mg
$ 75.00

Matrix Scientific
1-(Thien-2-ylcarbonyl)piperidin-4-one
500mg
$ 95.00

Crysdot
1-(Thiophene-2-carbonyl)piperidin-4-one 95+%
5g
$ 336.00

Chemenu
1-(thien-2-ylcarbonyl)piperidin-4-one 95%
10g
$ 504.00

Chemenu
1-(thien-2-ylcarbonyl)piperidin-4-one 95%
5g
$ 276.00

ChemBridge Corporation
1-(2-thienylcarbonyl)-4-piperidinone 95%
1 g
$ 46.00

American Custom Chemicals Corporation
1-(THIEN-2-YLCARBONYL)PIPERIDIN-4-ONE 95.00%
5G
$ 1016.40

American Custom Chemicals Corporation
1-(THIEN-2-YLCARBONYL)PIPERIDIN-4-ONE 95.00%
1G
$ 664.13

American Custom Chemicals Corporation
1-(THIEN-2-YLCARBONYL)PIPERIDIN-4-ONE 95.00%
0.5G
$ 616.00

AK Scientific
1-(Thien-2-ylcarbonyl)piperidin-4-one
500mg
$ 178.00

Total 9 raw suppliers

Chemical Property of 1-(Thiophene-2-carbonyl)piperidin-4-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:389.208oC at 760 mmHg
Flash Point:189.186oC
PSA：65.62000
Density:1.304g/cm3
LogP:1.49110
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:209.05104977
Heavy Atom Count:14
Complexity:245

Purity/Quality:

98%min ^*data from raw suppliers

1-(Thien-2-ylcarbonyl)piperidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1=O)C(=O)C2=CC=CS2

Technology Process of 1-(Thiophene-2-carbonyl)piperidin-4-one

There total 2 articles about 1-(Thiophene-2-carbonyl)piperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 5271-67-0
2-Thiophenecarbonyl chloride

: 41979-39-9
4-piperidone hydrochloride

: 141945-71-3
1-(thien-2-oyl)-4-oxopiperidine

Guidance literature:: With sodium hydroxide; In toluene; for 0.5h;

Reference yield:

: 41661-47-6
piperidin-4-one

: 141945-71-3
1-(thien-2-oyl)-4-oxopiperidine

Guidance literature:: 2-thiophenylcarboxylic acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; dmap; In dichloromethane; at 20 ℃; for 2h;

piperidin-4-one; In dichloromethane; at 20 ℃; for 18h;

Reference yield: 50.0%

: 26306-64-9
2,4-dichloro-1-(2-aminophenoxy)benzene

: 141945-71-3
1-(thien-2-oyl)-4-oxopiperidine

: {4-[2-(2,4-dichloro-phenoxy)-phenylamino]-piperidin-1-yl}-thiophen-2-yl-methanone

Guidance literature:: 2,4-dichloro-1-(2-aminophenoxy)benzene; 1-(thien-2-oyl)-4-oxopiperidine; With sodium borohydride acetate; acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 168h;

With sodium hydrogencarbonate; In 1,2-dichloro-ethane;