(S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester

Base Information

• Chemical Name: (S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester
• CAS No.: 80680-98-4
• Molecular Formula: C₃₇H₄₆N₄O₈
• Molecular Weight: 674.794
• Mol file: 80680-98-4.mol

Synonyms:

Chemical Property of (S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester

There total 1 articles about (S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-isobutyl-5-oxo-4,5-dihydro-oxazol-2-ylmethyl)-carbamic acid benzyl ester (80680-99-5) + L-Lys(Z)-OBzl*HCl (114331-06-5) → Z-Gly-Leu-Lys(-Z)-OCH2Ph (70290-83-4) + (S)-6-Benzyloxycarbonylamino-2-[(R)-2-(2-benzyloxycarbonylamino-acetylamino)-4-methyl-pentanoylamino]-hexanoic acid benzyl ester (80680-98-4)

Guidance literature:

With 4-methyl-morpholine; In dichloromethane; at 23 ℃; Product distribution; dependence of asymmetric induction on solvent polarity and temperature;

DOI:10.1016/S0040-4039(01)81905-5

upstream raw materials:

(4-isobutyl-5-oxo-4,5-dihydro-oxazol-2-ylmethyl)-carbamic acid benzyl ester

L-Lys(Z)-OBzl*HCl