METHYL 3-AMINO-2-METHYLCROTONATE

Base Information

• Chemical Name: METHYL 3-AMINO-2-METHYLCROTONATE
• CAS No.: 14369-90-5
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.186
• Mol file: 14369-90-5.mol

Synonyms:3-Amino-2-methyl-crotonsaeure-aethylester;3-amino-2-methyl-but-2-enoic acid ethyl ester;ethyl 3-amino-2-methylbut-2-enoate;3-Amino-2-methyl-crotonsaeure-ethylester;ethyl 3-aminocrotonate;

Chemical Property of METHYL 3-AMINO-2-METHYLCROTONATE

Chemical Property:

• Melting Point: 50-51 °C
• Boiling Point: 233.6±13.0 °C(Predicted)
• PKA: 5.51±0.70(Predicted)
• PSA: 52.32000
• Density: 0.991±0.06 g/cm3(Predicted)
• LogP: 1.50240

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 3-AMINO-2-METHYLCROTONATE

There total 7 articles about METHYL 3-AMINO-2-METHYLCROTONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetylpropanoic acid ethyl ester (609-14-3) → Ethyl 3-amino-2-methyl-2-butenoate (14369-90-5)

Guidance literature:

With ammonia;

Reference yield:

(±)-ethyl 2,3-dimethyl-2H-azirine-2-carboxylate (14369-89-2) → Ethyl 3-amino-2-methyl-2-butenoate (14369-90-5)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1021/jo01350a005

Reference yield:

→ Ethyl 3-amino-2-methyl-2-butenoate (14369-90-5)

Guidance literature:

With ammonia;

upstream raw materials:

2-acetylpropanoic acid ethyl ester

ethyl aminocrotonate

methyl iodide

(±)-ethyl 2,3-dimethyl-2H-azirine-2-carboxylate

Downstream raw materials:

5,6-dimethyl-2-phenyl-3-m-tolyl-3H-pyrimidin-4-one

3-(2-chloro-phenyl)-5,6-dimethyl-2-phenyl-3H-pyrimidin-4-one

2,5,6-trimethyl-3-p-tolyl-3H-pyrimidin-4-one

3-ethyl-5,6-dimethyl-2-phenyl-3H-pyrimidin-4-one