Benzyl 2-oxopyrrolidine-1-carboxylate

Base Information

Chemical Name:Benzyl 2-oxopyrrolidine-1-carboxylate
CAS No.:14468-80-5
Molecular Formula:C12H13NO3
Molecular Weight:219.24
Hs Code.:
DSSTox Substance ID:DTXSID00448847
Nikkaji Number:J1.236.156D
Wikidata:Q82268024
Mol file:14468-80-5.mol

Synonyms:14468-80-5;Benzyl 2-oxopyrrolidine-1-carboxylate;1-(Benzyloxycarbonyl)-2-pyrrolidinone;1-Cbz-2-oxo-pyrrolidine;1-Pyrrolidinecarboxylic acid, 2-oxo-, phenylmethyl ester;1-Z-2-Pyrrolidinone;n-cbz-pyrrolidinone;N-CBZ-2-Pyrrolidinone;SCHEMBL520065;1-Z-2-Pyrrolidinone, 97%;DTXSID00448847;DVMZKGUWEAXMRT-UHFFFAOYSA-N;Benzyl2-oxopyrrolidine-1-carboxylate;MFCD12827413;AB91761;AS-80383;CS-0334073;FT-0712149;2-Oxopyrrolidine-1-carboxylic acid benzyl ester;W10757

Suppliers and Price of Benzyl 2-oxopyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Benzyl2-Oxopyrrolidine-1-carboxylate
50mg
$ 45.00

Sigma-Aldrich
1-Z-2-Pyrrolidinone 97%
5g
$ 159.00

Crysdot
Benzyl2-oxopyrrolidine-1-carboxylate 95+%
5g
$ 339.00

Chemenu
Benzyl2-oxopyrrolidine-1-carboxylate 95%
5g
$ 320.00

AK Scientific
1-Z-2-Pyrrolidinone
5g
$ 204.00

Acrotein
1-Cbz-2-oxo-pyrrolidine 97%
1g
$ 128.33

ACHEMBLOCK
1-Cbz-2-oxo-pyrrolidine 95%
500MG
$ 115.00

Total 11 raw suppliers

Chemical Property of Benzyl 2-oxopyrrolidine-1-carboxylate

Chemical Property:

Melting Point:32-36°C
Boiling Point:147 °C(Press: 0.1 Torr)
PKA:-2.26±0.20(Predicted)
Flash Point:>110℃
PSA：46.61000
Density:1?+-.0.06 g/cm3(Predicted)
LogP:1.88350
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:219.08954328
Heavy Atom Count:16
Complexity:271

Purity/Quality:

97% ^*data from raw suppliers

Benzyl2-Oxopyrrolidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 52/53
Safety Statements: 61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CC(=O)N(C1)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 2-oxopyrrolidine-1-carboxylate

There total 9 articles about Benzyl 2-oxopyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 616-45-5
2-pyrrolidinon

: 501-53-1,94274-21-2
benzyl chloroformate

: 14468-80-5
N-benzyloxycarbonylpyrrolidin-2-one

Guidance literature:: 2-pyrrolidinon; With n-butyllithium; In tetrahydrofuran;

benzyl chloroformate; In tetrahydrofuran;
DOI:10.1016/S0040-4039(01)00822-X

Reference yield: 100.0%

: 14468-80-5
N-benzyloxycarbonylpyrrolidin-2-one

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

In tetrahydrofuran; at 20 ℃; for 10h;