Benzenecarbodithioic acid, 4-methoxy-, 1-methyl-2-oxopropyl ester

Base Information

• Chemical Name: Benzenecarbodithioic acid, 4-methoxy-, 1-methyl-2-oxopropyl ester
• CAS No.: 144863-96-7
• Molecular Formula: C₁₂H₁₄O₂S₂
• Molecular Weight: 254.374
• Mol file: 144863-96-7.mol

Synonyms:

Chemical Property of Benzenecarbodithioic acid, 4-methoxy-, 1-methyl-2-oxopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenecarbodithioic acid, 4-methoxy-, 1-methyl-2-oxopropyl ester

There total 2 articles about Benzenecarbodithioic acid, 4-methoxy-, 1-methyl-2-oxopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

3-chloro-2-butanone (4091-39-8) + Triethylammonium 4-methoxydithiobenzoate (54255-00-4) → 3-Oxobutan-2-yl 4-methoxydithiobenzoate (144863-96-7)

Guidance literature:

In dichloromethane; at 20 ℃; for 22h;

Reference yield:

4-methoxyphenyl magnesium bromide (13139-86-1) → 3-Oxobutan-2-yl 4-methoxydithiobenzoate (144863-96-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Et₂O, 20 deg C

2: 39 percent / CH₂Cl₂ / 22 h / 20 °C

In dichloromethane;

Reference yield:

3-Oxobutan-2-yl 4-methoxydithiobenzoate (144863-96-7) → 3-(4-methoxyphenyl)-5,6-dimethyl-1,4,2-dithiazine (141077-30-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) H₂SO₄, 2) HPF₆ / 1) CHCl₃, -20 deg C, 0.3 h, then -15 to -5 deg C, 2.5 h, 2) H₂O, 20 deg C

2: 56 percent / iodine, aq. NH₃ / acetonitrile / 1.5 h / 20 °C / other 1,3-dithiolium salts; synthesis of 1,4,2-dithiazines by ring expansion of 1,3-dithiolium cations

With ammonium hydroxide; hexafluorophosphoric acid; sulfuric acid; iodine; In acetonitrile;

upstream raw materials:

3-chloro-2-butanone

Triethylammonium 4-methoxydithiobenzoate

4-methoxyphenyl magnesium bromide

Downstream raw materials:

2-(4-Methoxyphenyl)-4,5-dimethyl-1,3-dithiolium hexafluorophosphate

3-(4-methoxyphenyl)-5,6-dimethyl-1,4,2-dithiazine

Refernces