(2E)-2-cyano-N-(furan-2-ylmethyl)-3-[5-(2-methyl-5-nitrophenyl)furan-2-yl]prop-2-enamide

Base Information

• Chemical Name: (2E)-2-cyano-N-(furan-2-ylmethyl)-3-[5-(2-methyl-5-nitrophenyl)furan-2-yl]prop-2-enamide
• CAS No.: 5949-37-1
• Molecular Formula: C20H15N3O5
• Molecular Weight: 377.3502
• Mol file: 5949-37-1.mol

Synonyms:

Chemical Property of (2E)-2-cyano-N-(furan-2-ylmethyl)-3-[5-(2-methyl-5-nitrophenyl)furan-2-yl]prop-2-enamide

Chemical Property:

• Vapor Pressure: 2.88E-16mmHg at 25°C
• Boiling Point: 639.8°Cat760mmHg
• Flash Point: 340.8°C
• Density: 1.337g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2E)-2-cyano-N-(furan-2-ylmethyl)-3-[5-(2-methyl-5-nitrophenyl)furan-2-yl]prop-2-enamide

There total 4 articles about (2E)-2-cyano-N-(furan-2-ylmethyl)-3-[5-(2-methyl-5-nitrophenyl)furan-2-yl]prop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

3-pyridinecarbonyl chloride (10400-19-8) + 2,2,6,6-tetramethylolcyclohexanol (5416-55-7) → nicomol (27959-26-8,5949-37-1)

Guidance literature:

at 70 - 80 ℃; Temperature;

Reference yield:

cyclohexanol (108-93-0) → nicomol (27959-26-8,5949-37-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; sodium dichromate / water / 0.5 h / 1 - 55 °C

2: calcium(II) nitrate; aluminium trinitrate; zinc(II) nitrate; sodium carbonate; sodium hydroxide / water / 2.5 h / 8 - 35 °C

3: 70 - 80 °C

With aluminium trinitrate; zinc(II) nitrate; sodium dichromate; sulfuric acid; calcium(II) nitrate; sodium carbonate; sodium hydroxide; In water;

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → nicomol (27959-26-8,5949-37-1)

Guidance literature:

Multi-step reaction with 2 steps

1: calcium(II) nitrate; aluminium trinitrate; zinc(II) nitrate; sodium carbonate; sodium hydroxide / water / 2.5 h / 8 - 35 °C

2: 70 - 80 °C

With aluminium trinitrate; zinc(II) nitrate; calcium(II) nitrate; sodium carbonate; sodium hydroxide; In water;

upstream raw materials:

3-pyridinecarbonyl chloride

2,2,6,6-tetramethylolcyclohexanol

cyclohexanol

cyclohexanone

Refernces