Benzenesulfonyl chloride, 4-bromo-2-methoxy-

Base Information

• Chemical Name: Benzenesulfonyl chloride, 4-bromo-2-methoxy-
• CAS No.: 145915-29-3
• Molecular Formula: C7H6BrClO3S
• Molecular Weight: 285.546
• Hs Code.: 2909309090
• Mol file: 145915-29-3.mol

Synonyms:4-Bromo-2-methoxybenzenesulfonyl chloride;

Chemical Property of Benzenesulfonyl chloride, 4-bromo-2-methoxy-

Chemical Property:

• Boiling Point: 329.2±27.0 °C(Predicted)
• PSA: 51.75000
• Density: 1.717±0.06 g/cm3(Predicted)
• LogP: 3.46600
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

4-Bromo-2-Methoxybenzene-1-SulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonyl chloride, 4-bromo-2-methoxy-

There total 3 articles about Benzenesulfonyl chloride, 4-bromo-2-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.7%

4-bromo-2-methoxyaniline (59557-91-4) → 4-bromo-2-methoxybenzene-1-sulfonyl chloride (145915-29-3)

Guidance literature:

With thionyl chloride; acetic acid; copper(l) chloride; sodium nitrite; In water; at -5 - 25 ℃; for 49h; Temperature;

Reference yield: 17.0%

3-methoxyphenyl bromide (2398-37-0) → 4-bromo-2-methoxybenzene-1-sulfonyl chloride (145915-29-3)

Guidance literature:

With chlorosulfonic acid; at -5 ℃; for 0.0833333h;

Reference yield: 5.0%

3-methoxyphenyl bromide (2398-37-0) → 4-bromo-2-methoxybenzene-1-sulfonyl chloride (145915-29-3) + 2-bromo-4-methoxybenzenesulfonyl chloride (23095-16-1)

Guidance literature:

With chlorosulfonic acid;

upstream raw materials:

3-methoxyphenyl bromide

4-bromo-2-methoxyaniline

Refernces

• 1、 -. "COMPOUNDS". Page/Page column 114. . Retrieved 2020/01/11.
• 2、 -. "PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS". Page/Page column 53. . Retrieved 2010/02/15.