Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate

Base Information

Chemical Name:Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate
CAS No.:146231-57-4
Molecular Formula:C14H18O6S
Molecular Weight:314.359
Hs Code.:
DSSTox Substance ID:DTXSID001179117
Mol file:146231-57-4.mol

Synonyms:DTXSID001179117;Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate;146231-57-4

Suppliers and Price of Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:314.08240946
Heavy Atom Count:21
Complexity:456

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C=C(C(=O)OC)S(=O)(=O)C1=CC=CC=C1)OCOC
Isomeric SMILES:CC(/C=C(\C(=O)OC)/S(=O)(=O)C1=CC=CC=C1)OCOC

Technology Process of Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate

There total 3 articles about Methyl (2E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 146231-56-3
(E)-4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentenoic acid

: 74-88-4
methyl iodide

: 146231-57-4
(E)-methyl 4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentanoate

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; for 4h; Ambient temperature;
DOI:10.1016/S0040-4039(00)60201-0 DOI:10.1016/S0040-4020(01)80181-2

Reference yield:

: 129083-19-8
(E)-1-benzenesulfonyl-1-buten-3-ol

: 146231-57-4
(E)-methyl 4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentanoate

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus pentoxide / CHCl₃ / 1.5 h / Ambient temperature

2: n-BuLi / hexane; tetrahydrofuran / 1 h / -78 °C

3: 88 percent / NaHCO₃ / dimethylformamide / 4 h / Ambient temperature

With phosphorus pentaoxide; n-butyllithium; sodium hydrogencarbonate; In tetrahydrofuran; hexane; chloroform; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)80181-2

Reference yield:

: ((E)-3-Methoxymethoxy-but-1-ene-1-sulfonyl)-benzene

: 146231-57-4
(E)-methyl 4-(methoxymethoxy)-2-(phenylsulfonyl)-2-pentanoate

Guidance literature:: Multi-step reaction with 2 steps

1: n-BuLi / hexane; tetrahydrofuran / 1 h / -78 °C

2: 88 percent / NaHCO₃ / dimethylformamide / 4 h / Ambient temperature

With n-butyllithium; sodium hydrogencarbonate; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)80181-2