Methanone, 1,2-phenylenebis[2-thienyl-

Base Information

• Chemical Name: Methanone, 1,2-phenylenebis[2-thienyl-
• CAS No.: 146474-88-6
• Molecular Formula: C16H10O2S2
• Molecular Weight: 298.386
• DSSTox Substance ID: DTXSID50448559
• Nikkaji Number: J1.578.312E
• Wikidata: Q82267610
• Mol file: 146474-88-6.mol

Synonyms:Methanone, 1,2-phenylenebis[2-thienyl-;146474-88-6;SCHEMBL9148337;DTXSID50448559;1,2-Bis(2-thienylcarbonyl)benzene

Chemical Property of Methanone, 1,2-phenylenebis[2-thienyl-

Chemical Property:

• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 298.01222190
• Heavy Atom Count: 20
• Complexity: 347

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C(=O)C2=CC=CS2)C(=O)C3=CC=CS3

Technology Process of Methanone, 1,2-phenylenebis[2-thienyl-

There total 7 articles about Methanone, 1,2-phenylenebis[2-thienyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

thiophen-2-yl magnesium bromide (5713-61-1) + benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester (162339-29-9) → 1,2-phenylene bis((thiophene-2-yl)methanone) (146474-88-6)

Guidance literature:

In tetrahydrofuran; at 0 ℃; for 0.666667h;

DOI:10.1021/ma400302j

Reference yield: 95.0%

2-bromothiophene (1003-09-4) + benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester (162339-29-9) → 1,2-phenylene bis((thiophene-2-yl)methanone) (146474-88-6)

Guidance literature:

2-bromothiophene; With iodine; magnesium; In tetrahydrofuran; at 0 ℃; for 3.5h;

benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester; In tetrahydrofuran; at 0 ℃; for 0.5h;

Reference yield: 92.0%

1,3-di(thiophen-2-yl)isobenzofuran (147438-00-4) → 1,2-phenylene bis((thiophene-2-yl)methanone) (146474-88-6)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 4h; Reagent/catalyst;

DOI:10.1055/s-0034-1378352

upstream raw materials:

1,2-phenylenebis(thiophen-2-ylmethanol)

2-bromothiophene

benzene-1,2-dicarbothioic acid di(S-pyridin-2-yl) ester

thiophen-2-yl magnesium bromide