tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate
CAS No.:147699-19-2
Molecular Formula:C13H25NO5S
Molecular Weight:307.411
Hs Code.:2933399090
ChEMBL ID:CHEMBL5017526
DSSTox Substance ID:DTXSID90570303
Wikidata:Q82457699
Mol file:147699-19-2.mol

Synonyms:147699-19-2;tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate;1-N-BOC-4-(2-METHANESULFONYLOXYETHYL)PIPERIDINE;tert-butyl 4-(2-methylsulfonyloxyethyl)piperidine-1-carboxylate;MFCD11007804;1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-, 1,1-dimethylethyl ester;tert-butyl 4-{2-[(methylsulfonyl)oxy]ethyl}piperidine-1-carboxylate;tert-butyl 4-[2-(methanesulfonyloxy)ethyl]piperidine-1-carboxylate;SCHEMBL310750;C13H25NO5S;CHEMBL5017526;DTXSID90570303;WSNYPQZNUKSYBI-UHFFFAOYSA-N;AKOS022172996;AM100258;AS-30150;CS-0199870;EN300-73605;A808676;1-tert-butoxycarbonyl-4-(2-mesyloxyethyl)piperidine;2-(1-tert-butoxycarbonylpiperidin-4-yl)ethyl mesylate;1-t-Butyloxycarbonyl-4-methanesulfonyloxyethylpiperidine;1-tert-butoxycarbonyl-4-(methylsulfonyloxy)ethyl piperidine;t-butyl 4-(2-((methylsulfonyl)oxy)ethyl)-1-piperidinecarboxylate;tert-butyl 4-(2-(methyl-sulfonyloxy)ethyl)piperidine-1-carboxylate;tert-butyl 4-(2-(methylsulfonyloxy)ethyl)piperidine-1-carboxylate;tert-butyl 4-{[(methylsulfonyl)oxy]ethyl}piperidine-1-carboxylate;tert-Butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate;1,1-dimethylethyl 4-{2-[(methylsulfonyl)oxy]ethyl}-1-piperidinecarboxylate;4-(2-methanesulfonyloxy-ethyl)piperidine-1-carboxylic acid tert-butyl ester;4-(2-methanesulfonyloxyethyl)piperidine-1-carboxylic acid tert-butyl ester;4-(2-methanesulfonyloxyethyl)piperidine-1-carboxylic acid tert-butylester;4-(2-methylsulfonyloxyethyl)-1-piperidinecarboxylic acid tert-butyl ester;tert-Butyl 4-{2-[(methanesulfonyl)oxy]ethyl}piperidine-1-carboxylate;tert-butyl 4-{2-[(methylsulfonyl)oxy]ethyl}-piperidine-1-carboxylate;4-[2-(methanesulfonyloxy)ethyl]piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-N-Boc-4-(2-methanesulfonyloxyethyl)piperidine
500mg
$ 155.00

Crysdot
tert-Butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate 97%
10g
$ 689.00

Crysdot
tert-Butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate 97%
5g
$ 459.00

Chemenu
tert-butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate 97%
5g
$ 429.00

Chemenu
tert-butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate 97%
10g
$ 644.00

American Custom Chemicals Corporation
1-BOC-4-(2-METHANESULFONYLOXY-ETHYL)- PIPERIDINE 95.00%
5G
$ 2181.31

American Custom Chemicals Corporation
1-BOC-4-(2-METHANESULFONYLOXY-ETHYL)- PIPERIDINE 95.00%
2.5G
$ 1635.30

American Custom Chemicals Corporation
1-BOC-4-(2-METHANESULFONYLOXY-ETHYL)- PIPERIDINE 95.00%
1G
$ 1070.84

AK Scientific
Tert-Butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate
1g
$ 547.00

AK Scientific
Tert-Butyl4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate
250mg
$ 264.00

Total 7 raw suppliers

Chemical Property of tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate

Chemical Property:

Boiling Point:431.1±18.0 °C(Predicted)
PKA:-1.54±0.40(Predicted)
PSA：81.29000
Density:1.154±0.06 g/cm3(Predicted)
LogP:3.01850
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:307.14534407
Heavy Atom Count:20
Complexity:413

Purity/Quality:

97% ^*data from raw suppliers

1-N-Boc-4-(2-methanesulfonyloxyethyl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)CCOS(=O)(=O)C

Technology Process of tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate

There total 11 articles about tert-Butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 124-63-0
methanesulfonyl chloride

: 89151-44-0
4-(2-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester

: 147699-19-2
tert-butyl 4-{2-[(methylsulfonyl)oxy]ethyl}piperidine-1-carboxylate

Guidance literature:: With triethylamine; In chloroform; at 20 ℃;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 147699-19-2
tert-butyl 4-{2-[(methylsulfonyl)oxy]ethyl}piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: NaH / tetrahydrofuran / 0 °C

2: H₂ / Pd/C / methanol / 20 °C

3: LAH / tetrahydrofuran / 20 °C

4: NEt₃ / tetrahydrofuran / 0 °C

With lithium aluminium tetrahydride; hydrogen; sodium hydride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/S0960-894X(03)00350-0