4-Trifluormethyl-N--anilin

Base Information

• Chemical Name: 4-Trifluormethyl-N--anilin
• CAS No.: 13406-25-2
• Molecular Formula: C₂₈H₁₆F₁₂NP
• Molecular Weight: 625.396

Synonyms:

Chemical Property of 4-Trifluormethyl-N--anilin

Chemical Property:

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Technology Process of 4-Trifluormethyl-N--anilin

There total 3 articles about 4-Trifluormethyl-N--anilin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(trifluoromethyl)phenylmagnesium bromide (402-51-7) → 4-Trifluormethyl-N--anilin (13406-25-2)

Guidance literature:

Multi-step reaction with 2 steps

1: PCl₃

With phosphorus trichloride;

Reference yield:

4-trifluoromethylphenylamine (455-14-1) → 4-Trifluormethyl-N--anilin (13406-25-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) aq. HCl, NaNO₂, (ii) NaN₃

Reference yield:

1-azido-4-(trifluoromethyl)benzene (5586-13-0) + tris(para-trifluoromethyl)phenyl phosphine (13406-29-6) → 4-Trifluormethyl-N--anilin (13406-25-2)

Guidance literature:

upstream raw materials:

1-azido-4-(trifluoromethyl)benzene

tris(para-trifluoromethyl)phenyl phosphine

4-trifluoromethylphenylamine

4-(trifluoromethyl)phenylmagnesium bromide

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