3,5-Dimethoxy-4-ethoxybenzoic acid

Base Information

• Chemical Name: 3,5-Dimethoxy-4-ethoxybenzoic acid
• CAS No.: 14779-44-3
• Molecular Formula: C11H14O5
• Molecular Weight: 226.229
• DSSTox Substance ID: DTXSID70545711
• Nikkaji Number: J1.321.563D
• Wikidata: Q82423296
• Mol file: 14779-44-3.mol

Synonyms:3,5-DIMETHOXY-4-ETHOXYBENZOIC ACID;14779-44-3;4-Ethoxy-3,5-dimethoxybenzoic acid;Benzoic acid, 4-ethoxy-3,5-dimethoxy-;SCHEMBL8638411;DTXSID70545711;IJMJUSXUKHSNJO-UHFFFAOYSA-N;3,5-dimethoxy-4-ethoxy-benzoic acid

Chemical Property of 3,5-Dimethoxy-4-ethoxybenzoic acid

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 226.08412354
• Heavy Atom Count: 16
• Complexity: 216

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=C(C=C(C=C1OC)C(=O)O)OC

Technology Process of 3,5-Dimethoxy-4-ethoxybenzoic acid

There total 9 articles about 3,5-Dimethoxy-4-ethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethyl 3,5-dimethoxy-4-ethoxybenzoate (75332-45-5) → 3,5-dimethoxy-4-ethoxybenzoic acid (14779-44-3)

Guidance literature:

ethyl 3,5-dimethoxy-4-ethoxybenzoate; With sodium hydroxide; water; In methanol; at 60 ℃; for 2h;

With hydrogenchloride; In methanol; water;

Reference yield:

4-ethoxy-3,5-dimethoxy-benzoic acid methyl ester (51210-04-9) → 3,5-dimethoxy-4-ethoxybenzoic acid (14779-44-3)

Guidance literature:

With hydrogenchloride; sodium hydroxide; In methanol;

Reference yield:

diethyl sulfate (64-67-5) + 3,5-dimethoxy-4-hydroxybenzoic acid (530-57-4) → 3,5-dimethoxy-4-ethoxybenzoic acid (14779-44-3)

Guidance literature:

With potassium hydroxide; ethanol; acetone;

upstream raw materials:

diethyl sulfate

3,5-dimethoxy-4-hydroxybenzoic acid

3,5-Dimethoxy-4-ethoxybenzaldehyde

1,3-dimethoxy-2-hydroxy-benzene

Downstream raw materials:

4-ethoxy-3,5-dimethoxy-benzoic acid methyl ester

4-ethoxy-3,5-dimethoxy-benzoic acid diethylamide

ethyl 3,5-dimethoxy-4-ethoxybenzoate

3,5-dimethoxy-4-ethoxybenzoyl chloride