Methyl 4-ethoxy-3,5-dimethoxybenzoate

Base Information

• Chemical Name: Methyl 4-ethoxy-3,5-dimethoxybenzoate
• CAS No.: 51210-04-9
• Molecular Formula: C12H16O5
• Molecular Weight: 240.25200
• DSSTox Substance ID: DTXSID80545909
• Nikkaji Number: J585.595K
• Wikidata: Q82423550
• Mol file: 51210-04-9.mol

Synonyms:51210-04-9;Methyl 4-ethoxy-3,5-dimethoxybenzoate;3,5-Dimethoxy-4-ethoxybenzoic acid methyl ester;SCHEMBL8639986;DTXSID80545909;MKQRZYXPRWXGAN-UHFFFAOYSA-N;methyl 3,5-dimethoxy-4-ethoxy-benzoate

Chemical Property of Methyl 4-ethoxy-3,5-dimethoxybenzoate

Chemical Property:

• PSA: 53.99000
• LogP: 1.88910
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 240.09977361
• Heavy Atom Count: 17
• Complexity: 229

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=C(C=C(C=C1OC)C(=O)OC)OC

Technology Process of Methyl 4-ethoxy-3,5-dimethoxybenzoate

There total 4 articles about Methyl 4-ethoxy-3,5-dimethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,5-dimethoxy-4-hydroxybenzoic acid (530-57-4) → 4-ethoxy-3,5-dimethoxy-benzoic acid methyl ester (51210-04-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH-solution

2: hydrogen chloride

With hydrogenchloride; sodium hydroxide;

Reference yield:

Eudesmic acid (118-41-2) → 4-ethoxy-3,5-dimethoxy-benzoic acid methyl ester (51210-04-9)

Guidance literature:

Multi-step reaction with 3 steps

1: fuming sulfuric acid / 33 - 40 °C

2: NaOH-solution

3: hydrogen chloride

With hydrogenchloride; sodium hydroxide; sulfuric acid;

Reference yield:

methanol (67-56-1) + 3,5-dimethoxy-4-ethoxybenzoic acid (14779-44-3) → 4-ethoxy-3,5-dimethoxy-benzoic acid methyl ester (51210-04-9)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

methanol

3,5-dimethoxy-4-ethoxybenzoic acid

3,5-dimethoxy-4-hydroxybenzoic acid

Eudesmic acid

Downstream raw materials:

3,5-dimethoxy-4-ethoxybenzoic acid