Phosphinic acid, diphenyl-, 2-hydroxyethyl ester

Base Information

• Chemical Name: Phosphinic acid, diphenyl-, 2-hydroxyethyl ester
• CAS No.: 14848-71-6
• Molecular Formula: C14H15O3P
• Molecular Weight: 262.245
• Mol file: 14848-71-6.mol

Synonyms:

Chemical Property of Phosphinic acid, diphenyl-, 2-hydroxyethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphinic acid, diphenyl-, 2-hydroxyethyl ester

There total 6 articles about Phosphinic acid, diphenyl-, 2-hydroxyethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

diphenyl-phosphinic acid (1707-03-5) + ethylene glycol (107-21-1) → 2-hydroxyethyl diphenylphosphinate (14848-71-6)

Guidance literature:

With copper(l) iodide; sodium carbonate; triethylamine; In tetrachloromethane; at 80 ℃; for 12h;

DOI:10.1021/cs501523g

Reference yield: 73.0%

ethylene glycol (107-21-1) + Diphenylphosphine oxide (4559-70-0) → 2-hydroxyethyl diphenylphosphinate (14848-71-6)

Guidance literature:

With trifluoromethylsulfonic anhydride; dimethyl sulfoxide; In ethanol; at 75 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c04127

Reference yield:

ethylene glycol (107-21-1) + Diphenylphosphinic chloride (1499-21-4) → 2-hydroxyethyl diphenylphosphinate (14848-71-6)

Guidance literature:

With pyridine; In tetrahydrofuran; Heating;

DOI:10.1016/S0040-4020(01)83312-3

upstream raw materials:

oxirane

diphenyl-phosphinic acid

ethylene glycol

Diphenylphosphinic chloride

Refernces

• 1、 -. "Preparation method of compound containing P-O bond or P-S bond". Paragraph 0212-0216. . Retrieved 2020/09/12.
• 2、 Xiong, Biquan,Feng, Xiaofeng,Zhu, Longzhi,Chen, Tieqiao,Zhou, Yongbo,Au, Chak-Tong,Yin, Shuang-Feng. "Direct aerobic oxidative esterification and arylation of P(O)-OH compounds with alcohols and diaryliodonium triflates". . p. 537 - 543. Retrieved 2015/04/14.